Brand Name:- Xtandi
Generic Name:- Enzalutamide
Alternative brand: Enzalu
Manufacturer:- Astellas
Dosage Form:- Capsules
Strength:- 40mg
Composition:- Enzalutamide
Packaging:- 120 capsules
Indication:- Prostate cancer
Storage:- Store at room temperature
Overview
Xtandi capsules are used to treat prostate cancer. Enzalutamide is a generic name for this medicine. This medicine belongs to the class of medications known as antineoplastic endocrine therapies. This medication works by blocking the effect of testosterone. Take this medicine with or without food. Your doctor will decide the exact dosage. Do not take this medicine in the wrong way as it may lead to some severe side effects. If you experience any symptoms while receiving this medicine, inform your doctor immediately. It is advisable not to change or stop the dose without taking suggestions from your doctor. This medicine is not recommended in children and females.
Pharmacodynamics Of Xtandi (Enzalutamide)
Enzalutamide is a competitive androgen receptor inhibitor that affects multiple stages of the signaling pathway. This inhibits androgen receptor nuclear translocation and interaction with DNA. Enzalutamide decreases proliferation and induced cell death of prostate cancer cells in vitro, and decreases tumor volume.
Side Effects Of Xtandi (Enzalutamide)
This medicine may cause some unwanted side effects. It requires immediate medical attention otherwise it can also lead to higher risk. Discuss the risks and benefits of this medication with the doctor before starting the treatment.
Common Side Effects
- Headache
- Weakness
- Back pain
- Fatigue
- Chest pain
- Loss of appetite
- Dizziness
- Fever
- Mouth sore
- Muscle weakness
- Anxiety
- Depression
- Seizures
- Diarrhea
- Nausea
- High blood pressure
- Irregular heartbeat
- Difficulty in breathing
- Blurred vision
- Itching
- Numbness
- Joint pain
- Drowsiness
- Vomiting
- Hot flashes
- Skin rash
- Allergic reaction
- Bleeding
- Low white blood cell count
- Bloating
- Pounding in the ears
- Sudden weight gain
- Painful urination
- Dry skin
Note-Immediately contact your doctor if any side effects occur
Dosage
Take this medicine as prescribed by your doctor. Do not chew or open the capsule. Take this medicine with or without food.
Missed Dose
- It is advisable not to miss a dose. If you miss a scheduled dose of Xtandi capsule, contact your doctor immediately.
Overdose
- In case of an overdose, the doctor will provide emergency medical treatment.
Usage Of Xtandi (Enzalutamide)
This medicine is used to treat CRPC (castrate-resistant prostate cancer, a stage where prostate cancer keeps growing) that has spread to other parts of the body. This medication prevents the action of androgens. Take this medicine orally once a day. Do not chew or open the capsule. The dose is decided by a medical advisor according to response to the treatment and your previous medical condition. Try not to miss your dosing schedule. Protect this medicine from heat and light.
Warnings
Before starting treatment with Xtandi, please inform your doctor about your previous medical history. If you experience any symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk.
- Children and adolescents
- This medicine is not advisable for use in children and adolescents.
Warnings For Female
- Pregnancy
- This medicine is not recommended in women.
- Breastfeeding
- This medicine is not recommended in women.
General Warnings And Precautions
- This medicine may cause neurological disorders.
- Close monitoring of kidney function is required during treatment with this medicine.
- This medication may increase the risk of falls, fractures, and serious injuries.
- Avoid driving because this medicine may cause dizziness.
- This medicine is not for use in children, adolescents, and females.
- This medicine may increase the risk of high blood pressure, diabetes, and high cholesterol.
- Avoid physical activities that may increase the risk of bleeding.
Cautions
- Do not chew, crush, or open the capsule.
- Do not drive or operate heavy machinery.
- Not for use in females.
- Not recommended in children and adolescents.
