Brand name – Virataz R
Generic name – Atazanavir/Ritonavir
Manufacturer – Hetero Drugs Ltd
Strength – 300 mg/100 mg
Dosage – Tablet (Oral administration
Packaging – Bottle
Indication – HIV infection
Description
Virataz R is a prescription medicine. It is a combination of two antiretrovirals namely Atazanavir and Ritonavir. This medicine is prescribed for the treatment of HIV (Human Immunodeficiency Virus) infection. It boosts up the immunity to fight against the virus and manage AIDS (Acquired Immunodeficiency Syndrome). It slows the growth of the virus in the body and reduces HIV-related symptoms, thereby improving the lifespan of individuals. This medicine is available at the best price in India.
Pharmacodynamics
Atazanavir:- it is an azapeptide HIV-1 protease inhibitor (PI) with activity against Human Immunodeficiency Virus Type 1 (HIV-1). HIV-1 protease is an enzyme required for the proteolytic cleavage of the viral polyprotein precursors into the individual functional proteins found in infectious HIV-1. Atazanavir works to bind to the protease active site and inhibit the activity of the enzyme. The inhibition prevents cleavage of the viral polyproteins resulting in the formation of immature non-infectious viral particles. Protease inhibitors are almost always used in combination with at least two other anti-HIV drugs.
Ritonavir:- It is a protease inhibitor with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Protease inhibitors block the part of HIV called protease. HIV-1 protease is an enzyme required for the proteolytic cleavage of the viral polyprotein precursors into the individual functional proteins found in infectious HIV-1. Ritonavir works to bind to the protease active site and inhibits the activity of the enzyme. The inhibition prevents cleavage of the viral polyproteins resulting in the formation of immature non-infectious viral particles.
Usage Of Medicine
Virataz R (Atazanavir/Ritonavir) tablet is prescribed to treat HIV (Human Immunodeficiency Virus) infection. It is available in the strength of 300 mg/100 mg in the form of tablets for oral administration. This medicine is not a cure for HIV. Also, it is not recommended for use in patients having a weight of less than 40 kg. It is advisable to not miss a dose or stop taking the medicine, without consulting the doctor.
Interactions
Interaction With Medicines
- Carbamazepine
- Cisapride
- Erythromycin
- Fluoxetine
- Loperamide
- Midazolam
- Cyclosporine
- Lovastatin
- Alprazolam
- Atorvastatin
Disease Interaction
- Liver Disease
- Diabetes
- Heart Disease
- Bleeding Disorders
Interaction With Alcohol
Interaction with alcohol is unknown. Make sure to consult your healthcare provider before consumption.
Contraindications
- Virataz R (Atazanavir/Ritonavir) tablet is contraindicated to the patents having an allergy to any of the ingredients of the medicine.
- It is not indicated to patients known to be hypersensitive.
Alternate Brands
- Anzavir-R
- Atazor R
- Synthivan
- Ataclip
Following are the side effects of Virataz R (Atazanavir/Ritonavir) tablet. Note that there can be other side effects also. Therefore, it is advisable to consult a medical practitioner if side effects occur or last longer than usual.
- Nausea
- Fever
- Chills
- Diarrhea
- Vomiting
- Stomach ache
- Skin rash
- Itching
- Taste change
- Weight loss
- Sweating
- Dry mouth
- Mood changes
- Difficulty in breathing
- Acid or sour stomach
- Redness of face
- High-cholesterol level
- Confusion
- High blood sugar level
- Drowsiness
- Blurred vision
- A feeling of warmth or heat
- Swelling on the face or neck
Normal Dose
Take Virataz R (Atazanavir/Ritonavir) tablet exactly in the same strength and duration as prescribed by your healthcare provider. Do not crush, break, chew or cut the tablet. Swallow it as a whole. Also, do not skip a dose.
Missed Dose
If you miss a dose, it is advisable to consult your healthcare provider to get the needed help. Also, make sure to not double the dose strength to catch up.
Overdose
It is advisable to seek emergency medical attention in case of overdose.
- Make sure to consult your healthcare provider regarding your medical history, medicines you already take, and allergies (if any).
- Administer Virataz R (Atazanavir/Ritonavir) tablet with caution in patients having known kidney or/and liver disease.
- During pregnancy or breastfeeding, make sure to discuss the potential risks and benefits of taking this medicine.
- Limit your sugar and salt intake.
- After taking Virataz R (Atazanavir/Ritonavir) tablet, avoid driving or operating heavy machinery if side effects like blurred vision or dizziness occur and last longer than usual.
- Blood glucose level should be closely monitored while consuming Virataz R (Atazanavir/Ritonavir) tablets.
