Medicine Details
Brand name – Velakast
Trade name – Epclusa
Generic name – Sofosbuvir/Velpatasvir
Company – Aprazer Healthcare
Manufacturer – Natco
Salt composition – Velpatasvir and Sofosbuvir
Storage – Store below 30°C
Dosage form – Oral (tablet)
Strength – 400mg + 100mg
Packaging – Bottle of 28 tablets
Gender – Unisex
Active ingredient – Velpatasvir and Sofosbuvir
Prescription required – Yes
Indication – Used to treat chronic Hepatitis C Virus (HCV) infection
Description
Velakast is a combination of Sofosbuvir and Velpatasvir, used to treat chronic (long-lasting) Hepatitis C Virus in adults. It slows the multiplication process of the virus and helps the immune system to fight against the infection. Velakast is a fixed dose tablet for oral administration. It is advised to take the dose everyday at the same time. It may help your liver to recover.
Pharmacodynamics
The effect of Sofosbuvir (Velakast) 400 mg (recommended dosage) and 1200 mg (three times the recommended dosage) on QTc interval was demonstrated in an active-controlled (moxifloxacin 400 mg) thorough QT trial. Sofosbuvir (Velakast) does not prolong QTc to any clinically relevant extent, at three times the recommended dose. The effect of Velpatasvir (Velakast) 500 mg (five times the recommended dosage) was demonstrated in an active-controlled (moxifloxacin 400 mg) thorough QT trial. Velpatasvir (Velakast) does not prolong QTc interval to any clinically relevant extent, at five times the recommended dose.
Ingredients
The active ingredient of Velakast is Sofosbuvir/Velpatasvir. The inactive ingredients are Titanium Dioxide IP and Brilliant Blue FCF, Polyethylene Glycol, Polyvinyl Alcohol, Talc and Titanium Dioxide.
Usage Of Medicine
Velakast (Velpatasvir and Sofosbuvir) tablet is used in the treatment of chronic Hepatitis C Virus (HCV) infection.
Alternate Brands
- Sovihep-v tablet
- Velasof tablet
- Velpanat tablet
- Hepcvel tablet
- Sofosvel talet
- Epclusa tablet
Dosage
Normal Dose
Your healthcare provider will prescribe you the dose. Take the dose exactly as prescribed, without any alteration/manipulation.
Missed Dose
If you miss a dose, take it as soon as you remember. If it is already the time for the next dose, do not take 2 doses. Do not double the doses to catch up.
Overdose
Please contact your healthcare provider immediately.
Warning And Precautions
- Consult your healthcare provider before taking this medicine. Do not decide your dose on your own. Make sure to take the exact dose as your doctor tells you. Do not alter or increase the strength of the dose, unless your healthcare provider tells you.
- Avoid drinking alcohol.
- Make sure to tell your doctor about your medical history and the medicines you already take because Velakast may cause adverse reactions with other medicines.
- If you have kidney disease, tell your doctor before starting the course. You may need dose alterations in that case.
- It is advised to tell your doctor if you have liver disease, before taking this medicine.
- Avoid driving and operating heavy machines, unless you are feeling well. Velakast may cause side effects like drowsiness, that may affect your concentration level.
