Brand name – Truvada
Generic name – Emtricitabine/Tenofovir Disoproxil Fumarate
Manufacturer – Abbott
Strength – 200 mg/300 mg
Dosage – Tablet (Oral administration)
Packaging – Bottle
Indication – HIV infection
Prescription needed – Yes
Description
Truvada (Emtricitabine/Tenofovir Disoproxil Fumarate) tablet is a prescription medicine. It is used in the treatment of HIV (Human Immunodeficiency Virus) infection. It boosts up the immunity to fight against the virus and manage AIDS (Acquired Immunodeficiency Syndrome). It slows the growth of the virus in the body and reduces HIV-related symptoms, thereby improving the lifespan of individuals. It increases the CD4 cell (white blood cells that protect against infection) count in the blood. This medicine is available at the best price in India.
Pharmacodynamics
Emtricitabine:- A synthetic nucleoside analog of cytidine, is phosphorylated by cellular enzymes to form Emtricitabine 5′-triphosphate. Emtricitabine inhibits the activity of the HIV-1 reverse transcriptase (RT) by competing with the natural substrate deoxycytidine 5′-triphosphate and by being incorporated into nascent viral DNA which results in chain termination.
Tenofovir Disoproxil Fumarate:- An acyclic nucleoside phosphonate diester analog of adenosine monophosphate. inhibits the activity of HIV-1 RT by competing with the natural substrate deoxyadenosine 5′-triphosphate and, after incorporation into DNA, by DNA-chain termination.
Usage Of Medicine
Truvada tablet is a combination of two antiretroviral agents namely Emtricitabine and Tenofovir Disoproxil Fumarate. This medicine is available in the strength of 200 mg/300 mg in the form of tablets for oral administration. It may be prescribed with other medications to treat HIV. It is important to take this medicine regularly at the right time for better efficacy. Also, it is advisable to not miss a dose. Make sure to report the side effects to the doctor (if any).
Interactions
Medicine interactions should be discussed with the healthcare provider before taking the Truvada (Emtricitabine/Tenofovir Disoproxil Fumarate) tablet.
Interaction With Alcohol
Interaction with Alcohol is unknown. Please consult your healthcare provider before consumption.
Interaction With Medicine
- Efavirenz
- Lamivudine
- Methotrexate
- Cisplatin
- Gentamicin
- Leflunomide
- Aspirin
- Tobramycin
Disease Interaction
- Hepatic impairment
- Renal Dysfunction
Contraindications
- Allergy – Truvada (Emtricitabine/Tenofovir Disoproxil Fumarate) tablet is not indicated for use in patients with a known allergy to Tenofovir, Emtricitabine, or any other ingredient of this medicine.
- Severe renal impairment – Truvada (Emtricitabine/Tenofovir Disoproxil Fumarate) tablet is not indicated for use in patients with severe renal impairment.
Alternate Brands
- Ricovir EM
- Forstavir EM
- Tenof EM
- Tofocom
- Tavin EM
Following are the side effects of Truvada (Emtricitabine/Tenofovir Disoproxil Fumarate) tablet. Note that there can be other side effects also. Therefore, it is advisable to consult a medical practitioner if side effects occur or last longer than usual.
- Fever
- Chills
- Peripheral neuropathy
- Stomach ache
- Diarrhea
- Blood in urine
- Fast heartbeat
- Irritation
- Loss of appetite
- Hoarseness
- Dizziness
- Unusual sweating
- Skin rash
- Itching
- Indigestion
- Constipation
- Redness of skin
- Headache
- Taste change
- Blurred vision
- Confusion
- Weight loss
- Sweating
- Mood changes
- Nausea
Normal Dose
Take Truvada (Emtricitabine/Tenofovir Disoproxil Fumarate) tablet exactly in the same strength and duration as prescribed by your healthcare provider. Do not crush, break, chew or cut the tablet. Swallow it as a whole. Also, do not skip a dose.
Missed Dose
If you miss a dose, it is advisable to consult your healthcare provider to get the needed help. Also, make sure to not double the dose strength to catch up.
Overdose
It is advisable to seek emergency medical help in case of overdose.
- Make sure to consult a medical practitioner regarding your medical history, medicines you already take, and allergies (if any).
- It is advisable to administer Truvada (Emtricitabine/Tenofovir Disoproxil Fumarate) tablet cautiously in patients having known kidney or/and liver disease.
- During pregnancy or breastfeeding, make sure to discuss the potential risks and benefits of taking this medicine.
- Limit your sugar and salt intake.
- After taking Truvada (Emtricitabine/Tenofovir Disoproxil Fumarate) tablet, it is advisable to avoid driving or operating heavy machinery if side effects like blurred vision or dizziness occur and last longer than usual.
- Blood glucose level should be closely monitored while consuming Truvada (Emtricitabine/Tenofovir Disoproxil Fumarate) tablets.
