Brand Name: Tenvir
Generic Name: Tenofovir Disoproxil Fumarate
Manufacturer: Cipla
Dosage Form: Tablet
Strength: 300mg
Composition: Tenofovir Disoproxil Fumarate
Indication: HIV
Storage: Store at room temperature
Overview
Tenvir (Tenofovir Disoproxil Fumarate) tablet is used in the treatment of HIV (Human immunodeficiency virus) infection. This medication helps to reduce the amount of HIV in your body and improves the quality of life. It boosts your immune system to fight against infection and prevents the virus from multiplying. It increases the CD4 cell (white blood cells that protect against infection) count in your blood. Do not take this medicine in the wrong way as it may lead to some serious side effects. If you experience any signs and symptoms while receiving this medicine, inform your doctor immediately.
Pharmacodynamics
Tenofovir disoproxil fumarate is an acyclic nucleoside phosphonate diester analog of adenosine monophosphate. It requires initial diester hydrolysis for conversion to tenofovir and subsequent phosphorylations by cellular enzymes to form tenofovir diphosphate. Tenofovir diphosphate works to inhibit the activity of HIV-1 RT by competing with the natural substrate deoxyadenosine 5′-triphosphate and, after incorporation into DNA, by DNA chain termination. It is a weak inhibitor of mammalian DNA polymerases alpha, beta, and mitochondrial DNA polymerase gamma.
Usage
Tenvir tablet contains Dolutegravir as an active ingredient. This medication is not a permanent cure for HIV infection. It only prevents the multiplication of HIV (human immunodeficiency virus) infection in human cells. The recommended dose of Tenvir medicine is decided by a doctor according to your previous medical condition and response to the treatment. It is important to take this medicine as prescribed by your doctor. It is advisable not to change your regular dosing schedule without taking suggestions from your doctor. The recommended dose of Tenvir medicine is decided by a doctor according to your previous medical condition and response to the treatment.
Interactions
Tenvir tablets can interact with other medications and it may increase the risk for side effects. Don’t forget to disclose and discuss your previous medical history with the doctor.
Medicine Interactions
- Cisplatin
- Tobramycin
- Gentamicin
- Darunavir
Disease Interactions
- Renal dysfunction
- Hepatic Impairment
Alcohol Interaction
- Interaction with alcohol is unknown. Please consult your doctor before consuming alcohol.
Contraindication
- Do not take this medicine if you are allergic to Tenofovir disoproxil fumarate.
- Tenvir tablet is not recommended in patients known to be hypersensitive.
Side Effect
This medicine may cause some common side effects. Discuss the risks and benefits of the Tenvir tablets with the doctor before starting the treatment.
Common Side Effects
- Trouble sleeping
- Loss of strength
- Fatigue
- Sore throat
- Swollen lymph nodes
- Loss of appetite
- Seizures
- Cough
- Unusual weakness
- Blurred vision
- Loss of weight
- Nausea
- Insomnia
- Diarrhea
- Blood in urine
- Irregular heartbeat
- Abnormal dream
- Confusion
- Indigestion
- Constipation
- Redness of skin
- Taste changes
- Unusual tiredness
- Fever
- Chills
Note – immediately contact your health care provider if any side effects occur.
Dosage
Take this medicine as prescribed by your doctor. Do not stop or skip your regular dosing schedule.
Missed Dose
- It is advisable not to miss a dose. If you miss a scheduled dose of Tenvir tablets, contact your doctor immediately.
Overdose
- In case of an overdose of Tenvir tablets, the doctor will provide emergency medical treatment.
Warning
Before starting treatment with Tenvir medicine, please inform your doctor about your previous medical history. If you experience any signs and symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk.
- Contraception
- Use suitable methods of contraception to prevent pregnancy while taking Tenvir medicine.
- Children and adolescents
- Tenvir tablets are not recommended for use in children under the age of 18.
Warnings For Female
- Pregnancy
- Do not use Tenvir medicine if you are planning to become pregnant. Avoid this medication at the time of pregnancy.
- Breastfeeding
- This medicine is not recommended in breastfeeding unless it is required. Please consult with your doctor before starting treatment with Tenvir (Tenofovir Disoproxil Fumarate).
Precautions
- Tenvir increases the risk of lactic acidosis.
- Inform your doctor if you experience any side effects like- nausea, insomnia, fever, sore throat, headache, abnormal dream, anxiety, etc.
- This medication may increase the risk of immune reconstitution syndrome.
- Close monitoring of bone mineral density is required during treatment with this medicine.
Cautions
- Do not drive or operate heavy machinery.
- Do not crush or break the tablet.
- Not safe for pregnant women.
- Do not breastfeed while receiving this medication.
