Brand Name: T-Lamirenz
Generic Name: Lamivudine + Tenofovir disoproxil fumarate + Efavirenz
Manufacturer: Arechar
Dosage Form: Tablet
Strength: 300mg/300mg/600mg
Composition: Lamivudine (300mg) + Tenofovir disoproxil fumarate (300mg) + Efavirenz (600mg)
Indication: HIV
Packaging: 30 tablet
Storage: Store at room temperature
Overview
Lamivudine, Tenofovir disoproxil fumarate, and Efavirenz are active ingredients that are used in the treatment of HIV, and together they form a tablet known as T-Lamirenz and these ingredients work in a combination to prevent HIV infection. This tablet belongs to a class of medications known as NRTIs (nucleoside reverse transcriptase inhibitors). T-Lamirenz boosts your immune system to fight against the infection.
Pharmacodynamics
Lamivudine (T-Lamirenz):- It is a nucleoside reverse transcriptase inhibitor with activity against HIV Type 1 and Hepatitis B Virus in order to disrupt viral DNA synthesis. When phosphorylated, this compound can form active metabolites that compete for incorporation into viral DNA. Through this process, Lamivudine metabolites work to inhibit the activity of the HIV reverse transcriptase enzyme. They act as a chain terminator of DNA synthesis.
Tenofovir Disoproxil Fumarate (T-Lamirenz):- This is particularly a nucleoside (acyclic) phosphonate diester analog of adenosine monophosphate. It usually requires initial diester hydrolysis in order to convert it to tenofovir and subsequent phosphorylations through cellular enzymes and form tenofovir diphosphate. It works to inhibit the activity of HIV-1 RT by competing with the natural substrate deoxyadenosine 5′-triphosphate and, after incorporation into DNA, by DNA chain termination.
Efavirenz (T-Lamirenz):- It is an oral non-nucleoside reverse transcriptase inhibitor. This compound is a synthetic purine derivative. It is similar to zidovudine stavudine. It was originally approved to treat HIV infections and AIDS in patients who failed therapy with zidovudine.
Usage
T-Lamirenz (Lamivudine + Tenofovir disoproxil fumarate + Efavirenz) anti-HIV tablet is used to stop the growth of HIV (human immunodeficiency virus) infection. This medicine decreases the risk of catching more infections. It is advisable to take this medicine as prescribed by your medical practitioner and do not skip your regular dosing schedule. It is necessary to inform your doctor if you have a history of cardiac disease or liver disease.
Interactions
T-Lamirenz tablets may interact with other medicines, diseases, and other elements. It is important to know the same before starting the course of this medicine.
Medicine Interactions
- Ciprofloxacin
- Methotrexate
- Aspirin
- Fluconazole
- Cisplatin
- Amiodarone
- Tobramycin
Disease Interactions
- Hepatoxicity
- CNS disorders
- Renal dysfunction
Alcohol Interaction
T-Lamirenz may or may not interact with alcohol. Please consult a qualified doctor before consuming alcohol.
Contraindication
- Do not administer T-Lamirenz tablets if you have an allergy to Lamivudine, Efavirenz, and Tenofovir Disoproxil Fumarate.
- T-Lamirenz tablets are not indicated for use in patients suffering from hypersensitivity.
- T-Lamirenz tablets are not recommended for use in patients suffering from kidney impairment.
Side Effects
T-Lamirenz (Lamivudine, Tenofovir disoproxil fumarate, and Efavirenz) tablets may cause certain side effects. Make sure to inform a qualified healthcare professional about the same and know the ways to manage them.
Common Side Effects
- Headache
- Tiredness
- Loss of weight
- Nausea
- Insomnia
- Diarrhea
- Blood in urine
- Irregular heartbeat
- Abnormal dream
- Fever
- Chills
- Loss of strength
- Fatigue
- Sore throat
- Unusual weakness
- Blurred vision
- Indigestion
- Constipation
- Redness of skin
- Abdominal pain
- Heartburn
Note – consult your pharmacist or healthcare professional if any possible side effects occur.
Dosage
Take the T-Lamirenz tablets exactly as prescribed by a qualified doctor. Do not crush or chew the tablet. Be sure to avoid skipping a dose.
Missed Dose
If you miss a dose, consult a qualified doctor. Do not increase the strength of the next dose to cope.
Overdose
In case of overdose, be sure to consult a healthcare professional or a medical helpline for proper monitoring.
Warnings
General Warnings
- Do not administer T-Lamirenz tablets without a prescription.
- Tell your doctor about the medicines you take before consuming T-Lamirenz tablets.
- If you are suffering from liver or/and kidney disease, avoid the consumption of T-Lamirenz tablets, until your healthcare provider prescribes.
Warnings For Female
Pregnancy
- During pregnancy, T-Lamirenz tablets may cause harm to the developing baby.
Breastfeeding
- During breastfeeding, T-Lamirenz tablets may cause harm to the developing baby.
Precautions
- Use proper contraceptive measures in order to avoid pregnancy during the course of this medicine.
- Know about the risks and benefits of taking T-Lamirenz tablets before their consumption.
- If side effects last longer than usual, inform your doctor about the same and know the ways to manage them.
Cautions
- Do not crush the T-Lamirenz tablets.
- Avoid missing a dose.
- Do not increase or decrease the dose strength as per your own wish.
- Avoid smoking and alcohol consumption during treatment with this medicine.
