Brand Name: Sovihep-V
Generic Name: Sofosbuvir and Velpatasvir
Manufacturer: Zydus
Dosage Form: Tablet
Strength: 100mg/400mg
Composition: Sofosbuvir 400mg + Velpatasvir 100mg
Packaging: 28 tablets per bottle
Indication: Hepatitis C
Storage: Store at room temperature
Overview
Sovihep V tablet is a combination of two antiviral drugs Sofosbuvir and Velpatasvir. This medicine is used in the treatment of chronic Hepatitis C virus (HCV). It works by blocking different steps in the reproduction of viruses. Do not take this medicine in the wrong way as it may lead to some severe side effects. It is advisable not to change or stop the dose without taking suggestions from your doctor. If you experience any symptoms while receiving this medicine, inform your doctor immediately. Store this medicine at room temperature and keep it away from light and moisture.
Pharmacodynamics Of Sovihep-V
Sofosbuvir With Velpatasvir is an oral fixed-dose combination of sofosbuvir, a nucleotide analog NS5B polymerase inhibitor, and Velpatasvir, an NS5A replication complex inhibitor. Sofosbuvir is approved for the treatment of genotype 1, 2, 3, and 4 HCV infection with different regimens and durations depending on the HCV genotype. After the oral administration, the effect of this medicine can be observed in 2 to 4 hours.
Usage Of Sovihep-V
Sofosbuvir and Velpatasvir are antiviral medications that are used in combination to treat Hepatitis C virus (HCV). The use of this medication reduces the amount of HCV in the body and helps our immune system to fight against infection. Take this medicine with or without food orally once a day. This medication may take some time to show effect. Do not miss your regular dosing schedule. The recommended dose is decided by a doctor according to your previous medical condition and response to the treatment.
Interactions Of Sovihep-V
Interactions may change how your medication works and increase the risk for side effects. Don’t forget to disclose your previous medical history with the doctor.
Medicine Interactions
- Carbamazepine
- Fosphenytoin
- Dexamethasone
- Lorlatinib
- Rifampicin
- St. john’s wort
Disease Interactions
- Immunosuppression
- Renal impairment
- Hepatic impairment
Alcohol Interaction
- Interaction with alcohol is unknown. Please consult your doctor before consuming alcohol.
Contraindications
- Do not take this medicine if you are allergic to Sofosbuvir and Velpatasvir.
- This medicine is not recommended in patients known to be hypersensitive.
Side Effects Of Sovihep-V
This medicine may cause some mild or severe side effects. Discuss the risks and benefits of this medication with the doctor before starting the treatment.
Common Side Effects
- Headache
- Diarrhea
- Nausea
- Tiredness
- Difficulty in breathing
- Cough
- Loss of appetite
- Muscle pain
- Rash
- Back pain
- Loss of strength
- Irregular heartbeat
- Chest pain
- Dizziness
- Unusual tiredness
- Slow heart rate
- Irritability
- Fatigue
- Anemia
- Chills
- Unusual weakness
- Itching
- Blurred vision
- Cramps
- Allergic reaction
- Insomnia
- Pale skin
Note- immediate medical attention is required if any side effect occurs
Dosage Of Sovihep-V
Take this medicine as prescribed by your doctor. Do not skip or miss your dosing schedule. This medicine can be taken with or without food.
Missed Dose
- It is advisable not to miss a dose. If you miss a scheduled dose of this medicine, contact your doctor immediately.
Overdose
- In case of an overdose, the doctor will provide emergency medical treatment.
Warnings Of Sovihep-V
Before starting treatment with this medication, please inform your doctor about your previous medical history. If you experience any symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk.
Contraception
- Use effective methods of contraception to prevent pregnancy while taking this medicine.
Children and adolescents
- This medicine is not advisable for use in children and adolescents.
Warnings For Female
Pregnancy
- Do not use this medicine if you are pregnant or planning to become pregnant. Avoid this medication at the time of pregnancy.
Breastfeeding
- This medicine is not recommended in breastfeeding unless it is necessary. Please consult your medical advisor before starting treatment with this medication.
Precautions Of Sovihep-V
- This medicine is not recommended in patients who have a history of Hepatitis B infection.
- Regular monitoring of liver function and the amount of hepatitis C virus (HCV) in your body is required.
- Close monitoring of kidney function is required.
- Inform your doctor if you experience any side effects like nausea, fatigue, headache, anemia, and rashes.
- Do not stop taking this medicine without your doctor’s advice.
- Contact your doctor if you have complications in the liver other than HCV infection.
Cautions Of Sovihep-V
- Do not drive or operate heavy machinery.
- Do not skip the regular dosing schedule.
- Not safe for pregnant women.
- Do not breastfeed while receiving this medication.
- Do not crush or break the tablet.
