Brand Name:- Sorafenat
Generic Name:- Sorafenib
Manufacturer:- Natco
Dosage Form:- Tablet
Strength:- 200mg
Composition:- Sorafenib
Packaging:- 120 tablet (120 / bottle)
Indication:- Kidney cancer, Liver cancer, and Thyroid cancer
Storage:- Store at room temperature
Overview
Sorafenat (Sorafenib) is used to treat a certain type of cancer (liver cancer, kidney cancer, and thyroid cancer). This tablet belongs to a class of medication known as a tyrosine kinase inhibitor. This medicine helps to stop the growth of cancerous cells. Take this medicine orally. Do not take this medicine in the wrong way as it may lead to some severe side effects. It is advisable not to change or stop the dose without taking suggestions from your doctor. If you experience any symptoms while receiving this medicine, inform your doctor immediately. Your doctor will decide the exact dosage of this medication.
Pharmacodynamics Of Sorafenat (Sorafenib)
Sorafenat is a kinase inhibitor that decreases tumor cell proliferation in vitro. Sorafenat inhibited tumor growth of HCC, RCC, and DTC human tumor xenografts in immunocompromised mice. Reductions in tumor angiogenesis were seen in models of HCC and RCC upon Sorafenat treatment, and increases in tumor apoptosis were observed in models of HCC, RCC, and DTC.
After the oral administration, the effect of this medicine can be observed in 3 hours.
Alternate Brands
- Sorafina
- Soranib
Side Effects Of Sorafenat (Sorafenib)
This medicine may cause some major and minor side effects. It requires immediate medical attention otherwise it can also lead to higher risk. Discuss the risks and benefits of this medication with a medical advisor before starting the treatment.
Common Side Effects
- Diarrhea
- Abdominal pain
- Fatigue
- Coughing up blood
- Bleeding gums
- Nausea
- Bloating
- Difficulty in breathing
- Irregular heartbeat
- Pale skin
- Seizures
- Sore throat
- Indigestion
- Hair loss
- Numbness
- Weight loss
- Dizziness
- Rash
- Joint pain
- Dry mouth
- Dehydration
- Anemia
- Fainting
- Lightheadedness
- Muscle cramps
- Anxiety
- Itching
- Vomiting
- Tiredness
- Difficulty in swallowing
- Weakness
- Chest pain
- Chills
Note- Immediately contact your doctor, if any side effects occur
Dosage
Take this medicine as prescribed by your doctor. Do not chew or crush the tablet. Take this medicine on an empty stomach.
Missed Dose
- It is advisable not to miss a dose. If you miss a scheduled dose of Sorafenat tablet, contact your doctor immediately.
Overdose
- In case of an overdose, the doctor will provide emergency medical treatment.
Usage Of Sorafenat (Sorafenib)
Sorfenat tablet works by slowing down the growth of cancer cells. Take this medicine orally on an empty stomach once a day. Try not to miss your regular dosing schedule. Take this medicine as prescribed by your medical advisor. Do not crush or chew the tablet. The dose is decided by a medical advisor according to response to the treatment and your previous medical condition. Regular monitoring of blood pressure is required during treatment with this medicine. Keep yourself hydrated and maintain good nutrition while having this medicine.
Warnings
Before starting treatment with Sorafenat, please inform your doctor about your previous medical history. If you experience any symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk.
- Contraception
- Use effective methods of contraception to prevent pregnancy while taking this medicine.
- Children and adolescents
- This medicine is not advisable for use in children and adolescents.
Warnings For Female
- Pregnancy
- Sorafenat tablets shouldn’t be used by pregnant women. Sorafenib may cause harm to the baby. It is recommended that this medicine should be avoided during pregnancy.
- Breastfeeding
- This medicine is not recommended in breastfeeding unless it is necessary. Please consult your medical advisor before starting treatment with this medication.
Precautions
- Regular monitoring of blood pressure is required during the treatment with this medicine.
- This medicine may increase the risk of bleeding.
- This medicine should be used with caution in patients with low blood glucose levels.
- Consult a doctor if you are suffering from heart diseases.
- This medication may cause dizziness.
- The use of this medicine may cause skin reactions.
- This medicine can reduce the number of white blood cells in the body.
- This medication may delay wound healing.
Cautions
- Do not drive or operate heavy machinery.
- Do not break, chew, or crush the medicine.
- Not safe for pregnant women.
- Do not breastfeed while receiving this medication.
- May harm liver
