Medicine Details
Brand name – Resof
Generic name – Sofosbuvir
Company – Dr. Reddy”s Laboratory
Salt composition – Sofosbuvir
Storage – Store at room temperature (10-30°C)
Dosage form – Oral (Tablet)
Strength – 400mg
Packaging – Bottle of 28 tablets
Gender – Unisex
Prescription needed – Yes
Active ingredient – Sofosbuvir 400mg
Indication – Used in the treatment of Chronic Hepatitis C Virus (HCV) infection
Description
Resof 400mg (Sofosbuvir) tablets are used with other medications in the treatment of chronic (long-lasting) Hepatitis C Virus in adults. It is advised to take Resof 400mg tablet exactly as the healthcare provider tells.
Pharmacodynamics
Sofosbuvir acts against Hepatitis C Virus. It is categorized as a direct-acting antiviral agent (DAA). At a dose (3 times the recommended dose), Sofosbuvir does not prolong QTc to any clinically relevant extent. Sofosbuvir is specifically a nucleotide analog inhibitor. It inhibits HCV NS5B (non-structural protein 5B) RNA-dependent RNA polymerase. Sofosbuvir incorporates into HCV RNA by the NS5B polymerase, following intracellular metabolism in order to form the pharmacologically active uridine analog triphosphate (GS-461203). Sofosbuvir prevents HCV viral implication and replication by binding to the two Mg2+ ions that are present in HCV NS5B polymerase’s GDD active site motif, thereby working to prevent further replication of HCV genetic material.
Ingredients
The active ingredient of Resof 400mg is Sofosbuvir. Sofosbuvir is used to treat viral infection of the liver. It helps to lower the multiplication of HCV.
Usage Of Medicine
Resof 400mg tablets are used in the treatment of chronic Hepatitis C Virus in adults, when administered with other supporting medications.
Alternate Brands
- Sofocure tablet
- Sovihep tablet
- Hepcvir tablet
- Hepcinat tablet
- Sofab tablet
- Sofovir tablet
Side Effects
Common Side Effects
- Tiredness
- Fever
- Difficulty in breathing
- Cough
- Lower back pain
- Headache
- Skin rash
- Irritability
- Insomnia
- Vomiting
Serious Side Effects
- Diarrhea
- Nausea
- Loss of appetite
- Muscle pain
- Cramps
- Anemia
Dosage
Normal Dose
Your healthcare provider will decide your dose, and duration of your dose. Please do not alter or manipulate the dose strength, unless your healthcare provider tells you.
Missed Dose
If you miss a dose, try to take it as soon as you remember. However, if it is already the time for the next dose, do not take the missed dose as it will double the dose strength.
Overdose
In case of overdose, seek emergency medical help.
Warning And Precautions
- Resof 400mg tablets should not be taken without doctor’s prescription.
- Make sure to tell your healthcare provider about all the medicines you already take, along with your medical history.
- Avoid drinking alcohol.
- Do not alter or manipulate the dose strength on your own, unless your healthcare provider tells you.
- Make sure to keep a note of the minor side effects you experience, and consult your healthcare provider for the same.
- During pregnancy or breastfeeding, kindly ask your healthcare provider if Resof is safe for you or not. Do not administer without doctor’s prescription.
- Do not crush, chew or break the tablet. Swallow it as a whole.
- Drink plenty of water.
Contraindication
You should not take Resof 400mg tablet unless your healthcare provider tells you, if you are suffering from:
- Liver or/and kidney disease
- HIV/AIDS
- Drug allergy
