PEG L-ASPARA

DESCRIPTION

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Medicine Details

Brand Name:- Peg L-Aspara
Generic Name:- Peg Asparaginase
Manufacturer:- Arechar Healthcare
Dosage:- Injection
Storage:- Store in a refrigerator.
Indication:- Blood Cancer
Prescription required:- Yes

Description

Peg L-Aspara is an anti-cancer medication. It is used in the treatment of Blood Cancer including Acute Lymphoblastic Leukemia. Peg L-Aspara (Peg Asparaginase) belongs to a group of medicines known as antineoplastic agents. It is used in combination with other anti-cancer medications for better efficacy. Peg L-Aspara is given by a medical practitioner as an injection. It is advised to not skip a scheduled dose.

Pharmacodynamics

The active ingredient of Peg L-Aspara is Peg Asparaginase. Asparaginase is an enzyme used in the treatment of acute lymphocytic leukemia (ALL). Pegasparginse is PEGylated with a high degree of polydispersity in its final formulation. Its molecular formula is C1377H2208N382O442S17 and its molar mass is 31732.06 g·mol-1.

Usage Of Medicine

Peg L-Aspara is a prescription medicine used to treat Acute Lymphoblastic Leukemia. It is available in the form of an injection. The active ingredient of Peg L-Aspara is Peg Asparaginase. It interferes with the processes that are responsible for the growth and production of cancer cells, thereby stopping the multiplication of such cells in the human body. Your healthcare provider will decide the dose strength and frequency of taking this medicine according to your medical condition.

Interactions

All the medicines interact in different manners from person to person. Therefore, it is advisable to consult a healthcare professional to discuss this before the consumption of any new medicine.

Interaction With Alcohol

Interaction with alcohol is unknown. Therefore, be sure to consult your doctor.

Interaction With Medicine

  • Adalimumab
  • Clozapine
  • Live attenuated vaccines and related products
  • Etanercept

Contraindications

  • Peg L-Aspara injection is not indicated for use in patients having an allergy to Asparaginase or any of the ingredients of Peg L-Aspara injection.
  • It is also not indicated to patients with pancreatitis.

Alternate

The side effects of Peg L-Aspara injection are mentioned below. It is important to consult a medical practitioner in case these/other side effects occur.

  • Headache
  • Fever
  • Chills
  • Weight loss
  • Stomach ache
  • Itching
  • Skin rash
  • Difficulty in breathing
  • Diarrhea
  • Fatigue
  • Nausea
  • Edema (swelling)
  • Tiredness
  • Drowsiness
  • Decreased blood pressure
  • Increased glucose level in the blood
  • Hives

Normal Dose

It is advisable to not self–administer Peg L-Aspara (Peg Asparaginse) injection. Your healthcare provider will give you this injection according to your medical condition.

Missed Dose

Initially, it is advisable to not miss a dose. However, if such a case happens, make sure to consult your healthcare provider to schedule an appointment for the same or guide you further.

Overdose

In case you experience symptoms of overdose, immediately call your doctor or any other medical emergency helpline

Warnings

Administer Peg L-Aspara (Peg Asparaginse) injection cautiously if you have or ever had any of the following diseases:

  • Kidney disease
  • Liver disease
  • Heart disease
  • High blood pressure
  • Thyroid disorders
  • Hepatic failure

Precautions

  • Contact a medical practitioner regarding the medicines you already take because those medicines may interact with L-Aspara (Peg Asparaginse) injection and may create complications.
  • Discuss the potential risks and benefits of taking L-Aspara (Peg Asparaginse) injection before their consumption.
  • Consult your doctor regarding the use of contraception during the course of this medicine.

Cautions

  • Avoid driving or operating heavy machinery after taking L-Aspara (Peg Asparaginse) injection.
  • Do not skip a dose.
  • Do not overdose.