Brand name: Lamipure
Generic name: Lamivudine
Strength: 150 mg
Manufacturer: Aprazer Healthcare
Dosage form: Tablets
Indication: HIV and Hepatitis B Virus
Storage: Store at room temperature.
Overview
Lamipure is a formulation of Lamivudine which is a nucleoside analog and reverse transcriptase inhibitor. It is used in the treatment of individuals diagnosed with HIV (Human Immunodeficiency Syndrome) infection and HBV (Hepatitis B Virus). The regimen is also used to treat or manage AIDS (Acquired Immunodeficiency Syndrome). Most doctors recommend Lamipure with other antiretroviral drugs for better recovery. Sometimes, it is also prescribed for the prevention of HIV infection. Lamipure (Lamivudine) tablets are available in the strength of 150 mg. It should be taken orally with a glass of water at the same time every day.
Pharmacodynamics
Lamivudine (Lamipure) is a synthetic nucleoside analog that is phosphorylated intracellularly to produce lamivudine triphosphate, an active 5′-triphosphate metabolite (L-TP). HIV reverse transcriptase and HBV polymerase integrate this nucleoside analog into viral DNA, causing DNA chain termination.
Interactions
Lamipure (Lamivudine) tablets can interact with other drugs, diseases, and alcohol. This can cause adverse effects. Thus, read the following before taking the regimen.
With Medicines
- Trimethoprim
- Zalcitabine
- Leflunomide
- Bexarotene
- Lomitapide
- Pexidartinib
- Methotrexate
- Mipomersen
- Remdesivir
- Tafamidis
- Teriflunomide
With Diseases
- Hepatotoxicity
- Pancreatitis
- Renal dysfunction
With Alcohol
- It is not known whether Lamipure (Lamivudine) interacts with alcohol. Contact your doctor for better guidance.
Contraindications
Lamipure (Lamivudine) tablets are contraindicated in the following cases:
- Acute or chronic inflammation of the pancreas
- Breastfeeding mother
- Chronic kidney disease
- Increased blood activity
Alternate Brands
The following are the substitutes for Lamipure (Lamivudine) tablets.
- Lamivir
- Heptavir
Lamipure (Lamivudine) tablets can lead to certain side effects post-administration. Some of them are given below.
- Cough
- Diarrhea
- Fatigue
- Stomach pain
- Diarrhea
- Shallow breathing
- Muscle pain
- Weakness
- Feeling cold or dizzy
- Headache
- Malaise (general discomfort)
- Sudden or severe rash
- Breathing problems
- Dark urine
- Loss of appetite
- Hives
- Nasal symptoms, like a runny nose
- Nausea
- Dizziness
- Drowsiness
- Joint pain
- Lightheadedness
Note: Seek emergency attention from a medical practitioner if severe allergic reactions occur or other side effects don’t go away.
Lamipure (Lamivudine) tablets should be ideally administered as a tablet once daily with other prescribed drugs with a glass of water.
Missed Dose
If you skip a dose of Lamipure (Lamivudine), you must contact your medical practitioner to know the ways of coping.
Overdose
In case of overdose on Lamipure (Lamivudine), you must contact your medical professional for better guidance and support.
Consult your medical professional if adverse events occur for a long period of time. Read the following warnings and precautions concerning the use of Lamipure (Lamivudine) tablets.
Warnings For Females
- Pregnancy
- Lamipure (Lamivudine) tablets may not be absolutely safe for use in pregnant females. Ask your health practitioner about the associated risks.
- Breastfeeding
- If your doctor recommends Lamipure (Lamivudine) tablets, make sure to avoid breastfeeding.
Precautions
- Contraception
- Use effective contraceptives and practice safe-sex practices during your treatment with Lamipure (Lamivudine).
- Dose
- Do not change the strength of your dose of Lamipure (Lamivudine). Take it as per the prescription. Also, do not skip a scheduled dose of antiretrovirals.
Caution
- Alcohol
- It is not known whether Lamipure (Lamivudine) interacts with alcohol. Contact your doctor for better guidance.
- Driving
- Lamipure (Lamivudine) tablets may cause severe side effects after administration. Avoid driving if you feel unwell.
