Brand name: Inlybest-1
Generic name: Axitinib
Strength: 1mg and 5mg
Manufacturer: Aprazer
Dosage form: Tablet
Indication: Kidney cancer
Storage: Store at room temperature.
Overview
Inlybest-1 contains Axitinib as an active substance and it is indicated for the treatment of renal cell carcinoma (a type of cancer that begins in the kidney). This anticancer formulation belongs to a group of medications known as tyrosine kinase inhibitors. Inlybest-1 is available in the form of a tablet and it works by blocking the action of an abnormal protein. Take this medicinal formulation orally and swallow the whole tablet with a glass of water. Follow your dosing instructions as prescribed by your general practitioner.
Pharmacodynamics
Axitinib helps in preventing the progression of cancer by causing inhibition of angiogenesis and blocking tumor growth. It selectively blocks the tyrosine kinase receptors VEGFR-1 (vascular endothelial growth factor receptor), VEGFR-2, and VEGFR-3. The formulation is mainly eliminated in the feces (about 41%) with nearly 12% of the original dose as unchanged axitinib. There is also 23% eliminated in the urine, most of which are metabolites.
Usage
This effective regimen is used to treat Kidney cancer and it helps in decreasing the spread of cancerous cells. Follow all the instructions carefully and administer the tablet as directed by your physician. Do not increase or decrease the strength of Inlybest-1 and for better efficacy complete your dosing schedule. Monitoring of blood pressure is required during treatment with Inlybest-1 (Axitinib) tablets.
Interactions
It is important to know the interactions of Inlybest-1 tablets with other drugs and diseases, before starting therapy with this ant-cancer formulation.
Medicine Interactions
- Carbamazepine
- Etravirine
- Leflunomide
- Rifampin
- Thalidomide
- Lorlatinib
Disease Interactions
- Hemorrhagic events
- Cardiac failure
- GI perforation
- Hypertension
- Proteinuria
- Thyroid dysfunction
- Lung toxicity
Alcohol Interactions
- Avoid consuming alcohol while receiving treatment with Inlybest-1 tablets.
Contraindications
The Inlybest-1 tablet is not indicated for use in the below-mentioned cases. Do not use this medication if any of the following apply to you:-
- Hypersensitive to the active ingredients present in the medication.
- Allergic to Axitinib.
Mild or major side effects may occur during treatment with Inlybest-1 tablets, if side effects last longer than usual inform your general practitioner as soon as possible.
Common Side Effects
- Mouth sores
- Stomach pain
- Heartburn
- Headache
- Dizziness
- Rash
- Itching
- Dry skin
- Pale skin
- Fast heartbeat
- Hair loss
- Ringing in the ears
- Thirst
- Hemorrhoids
- Wound or cut that will not heal
- Diarrhea
- Decrease in appetite
- Weight loss
- Nausea
- Vomiting
- Constipation
- Tiredness
- Weakness
- Redness
- Swelling
- Cough
- Joint or muscle pain
Note:- contact your medical professional if any side effects occur and don’t go away easily.
Take the Inlybest-1 tablet as prescribed by your health professional. Make sure to take this cancer-fighting formulation in the same amount as directed by your physician.
Missed Dose
If you miss a scheduled dose of Inlybest-1 tablet, contact your medical practitioner immediately to know the ways of coping with the missed or skipped dose.
Overdose
In case of an overdose, the patient is advised to consult a general practitioner as soon as possible if any unusual symptoms occur.
Warnings
Inform your physician if you have any pre-existing disorder. Check all the possible benefits and risks before starting treatment with the Inlybest-1 tablet.
Warnings For Females
Pregnancy
- Inlybest-1 (Axitinib) tablets are not recommended for use in pregnant women because they may affect the unborn baby.
Breastfeeding
- Do not use Inlybest-1 (Axitinib) tablets in breastfeeding. Talk to your medical provider before starting treatment with Inlybest-1.
Precautions
- Before starting treatment with Inlybest-1 medication, tell your general practitioner if you have skin problems like rash, redness, pain, blisters on the palm of your feet.
- Inform your healthcare expert if you have any pre-existing disorder of the heart.
- If you experience any allergic reaction after the first dose of Inlybest-1 (Axitinib), be sure to contact your general practitioner.
Cautions
- Do not drive or operate heavy machinery
- Do not skip a dose
- Do not take more or less of this medication
- Do not overdose
