Brand name: Indenza
Generic name: Enzalutamide
Strength: 40 mg
Manufacturer: Aprazer Healthcare
Dosage form: Capsules
Indication: Prostate Cancer
Storage: Store at room temperature.
Overview
Indenza comprises Enzalutamide as an active substance and it belongs to a class of medications androgen receptor inhibitors. This medication is prescribed for the treatment of Prostate cancer. Indenza tablets help in blocking the action of testosterone (male hormones) that convey the message to cancer cells. Administer this dosage formulation orally as prescribed by your healthcare practitioner.
Pharmacodynamics
Enzalutamide (Indenza) is a competitive androgen receptor inhibitor that influences multiple stages of the signaling pathway. It works by inhibiting androgen binding to its receptor, androgen receptor nuclear translocation, and subsequent interaction with DNA. As a result, the proliferation of prostate cancer cells decreases which ultimately leads to apoptosis and decreased tumor volume.
Usage
Indenza (Enzalutamide) acts by preventing testosterone from playing a role in the adrenal glands. The drug works by inhibiting androgen receptors on the surface of prostate cancer cells. Because the hormone is unable to attach to androgen receptors, cancer cells cannot proliferate anywhere in the body. Complete your dosing schedule as directed by your medical professional.
Interactions
Before the administration of Indenza (Enzalutamide) capsules, make sure to read the following interactions. Also, consult your medical professional.
With Medicines
Verapamil
Clozapine
Dexamethasone
Pimozide
With Diseases
Kidney impairment
Seizures
With Alcohol
The interaction of Indenza with alcohol is unknown. Be sure to contact your GP.
Alternate Brands
The following are the alternatives for Indenza (Enzalutamide) capsules.
Xtandi
Enzamide
Enzana
Enzalu
Contraindications
Indenza (Enzalutamide) capsules may not be prescribed in the following conditions.
Women
Hypersensitive patients
Allergic patients
Alternate Brands
Enzalu
Indenza (Enzalutamide) capsules may lead to certain side effects in some individuals. The below-mentioned effects are the most common ones.
- Numbness
- Headache
- Weakness
- High blood pressure
- Irregular heartbeat
- Difficulty in breathing
- Blurred vision
- Skin rash
- Allergic reaction
- Pounding in the ears
- Bleeding
- Low white blood cell count
- Bloating
- Joint pain
- Drowsiness
- Vomiting
- Hot flashes
- Sudden weight gain
- Painful urination
- Dry skin
- Nausea
- Itching
- Dizziness
- Fever
- Mouth sore
- Muscle weakness
- Anxiety
- Depression
- Seizures
- Diarrhea
- Back pain
- Fatigue
- Chest pain
- Loss of appetite
Administer Indenza (Enzalutamide) capsules orally with a glass of water. It can be taken with or without food as per the schedule prescribed by the health professional.
Missed Dose
If you miss a prescribed dose of Indenza (Enzalutamide) capsules, contact your medical professional right away to know the ways of coping with it.
Overdose
In case of an overdose, the individual is advisable to call a general practitioner immediately if any unusual severe symptom occurs.
- Women
Indenza (Enzalutamide) capsules are not recommended for use in women. - Children
Indenza (Enzalutamide) capsules are not recommended for use in children. - Kidney
Patients with kidney disease should administer Indenza (Enzalutamide) capsules with caution. - Liver
Patients with liver disease should administer Indenza (Enzalutamide) capsules with caution. - Contraception
Use effective contraceptives during your therapy with Indenza (Enzalutamide) capsules to prevent pregnancy. - Driving
After administering Indenza (Enzalutamide) capsules, do not drive if you feel sick. - Alcohol
The interaction of Indenza with alcohol is unknown. Be sure to contact your GP.
