EXEMPTIA

Brand name: Exemptia

Generic name: Adalimumab

Strength: 40mg/0.8ml

Manufacturer: Zydus Cadila

Dosage form: Injection

Indication: Rheumatoid arthritis

Storage: Store in a refrigerator

Overview

Exemptia (Adalimumab) is available in the form of injection and the strength of 40mg/0.8ml. This injection is used for the treatment of various conditions (rheumatoid arthritis, juvenile idiopathic arthritis, Crohn’s disease, ulcerative colitis). Exemptia injection works by blocking the action of chemical messengers, which are responsible for certain joint diseases. Before starting treatment, inform your physician if you have a history of heart, liver, and kidney disease. Do not self-administer Exemptia medication.

Pharmacodynamics

Adalimumab decreases the levels of acute-phase reactant proteins of inflammation (C­ reactive protein [CRP] and erythrocyte sedimentation rate [ESR]) and serum cytokines (IL-6) and it was compared to baseline in patients diagnosed with rheumatoid arthritis. In patients diagnosed with Crohn’s disease, a decreased level of CRP was also observed in them. Serum levels of matrix metalloproteinases (MMP-1 and MMP-3) that lead to the tissue remodeling responsible for cartilage destruction were also found to be decreased after administrating adalimumab in patients, reduction in signs and symptoms of disease, the induction of clinical response, and inhibition of structural damage, and improvements in physical function in adult and pediatric patients with various inflammatory conditions have been demonstrated.

Usage

Exemptia (Adalimumab) injection belongs to a class of medications known as biological response modifiers. This injection helps in relieving symptoms like swelling, pain, and redness which are caused by various disorders (rheumatoid arthritis, juvenile idiopathic arthritis, Crohn’s disease, ulcerative colitis, ankylosing spondylitis, uveitis, chronic plaque psoriasis, etc.). The use of Exemptia medication may result in the formation of autoantibodies in some patients, immediate discontinuation of treatment is recommended on such patients.

Interactions

Use of Exemptia (Adalimumab) injection may interact with other medications and it can cause some unusual side effects. Do not forget to discuss it with your healthcare provider.

Medicine Interactions

·         Budesonide

·         Azathioprine

·         Cisplatin

·         Betamethasone

·         Clozapine

·         Linezolid

·         Tacrolimus

·         Hydrocortisone

·         Cyclosporine

·         Triamcinolone

·         Altretamine

Disease Interactions

·         Malignancies

·         Congestive heart failure

·         Neurological disorders

·         Hepatitis B

·         Infections

·         Tuberculosis

 

Alcohol Interactions

·         Avoid consuming alcohol while receiving treatment with Exemptia (Adalimumab) 40mg/0.8ml injection because it may cause some side effects like dizziness.

Contraindications

·         Use of Exemptia injection is not recommended in patients who are allergic to Adalimumab r any other inactive ingredients.

·         Do not use Exemptia (Adalimumab) injection if you have a pre-existing problem of hypersensitivity.

Alternate medicine
Olumiant

Following are the possible side effects that can occur during your treatment with Exemptia (Adalimumab) injection. Contact your healthcare provider if they last longer.

 

• Nausea
• Injection site reactions
• Headache
• Back pain
• Vomiting
• Numbness
• Burning sensation
• Vision disturbances
• Weakness
• Chest pain
• Shortness of breath
• Tingling in the arms and feet
• Difficulty in swallowing
• Skin rash
• Chills
• Swelling
• Blurred vision
• Muscle pain
• Irregular heartbeat
• Bruising
• Itching
• Joint pain
• Fever
• Unusual bleeding
• Pale skin
• Red patches on the skin
• Heartburn
• Ear congestion
• Black or tarry stools
• Sleep disturbances
• Upper respiratory tract infection
• Difficulty in breathing

 

Note – contact your medical practitioner immediately if any of the above-mentioned side effects occur.

Exemptia (Adalimumab) injection is administered by a qualified nurse or medical professional and recommended dosage is decided by your physician according to your medical history and current health conditions.

Missed Dose

If you miss a scheduled dose of Exemptia (Adalimumab) contact your health professional as soon as possible. Try not to miss or skip your dosage of Exemptia injection.

Overdose

In case of an overdose of Exemptia (Adalimumab), contact your medical practitioner immediately in order to avoid severe side effects.