Brand Name: Emfovir
Generic Name: Tenofovir Disoproxil Fumarate & Emtricitabine
Manufacturer: Arechar Healthcare
Strength: 300mg,200mg
Dosage: Tablets
Indications: HIV
Storage: Store at room temperature
Overview
Emfovir is a combination of two medications and it contains Tenofovir Disoproxil Fumarate and Emtricitabine as active ingredients. This tablet specifically belongs to a group of medications known as antiretrovirals. This medication is used to treat HIV (human immunodeficiency virus) infection and managing AIDS (Acquired immunodeficiency syndrome). Emfovir tablets help in decreasing the amount of virus from the body. To avoid side effects like diarrhea and dizziness, keep yourself hydrated and get plenty of rest.
Pharmacodynamics
Emtricitabine (Emfovir): It is a synthetic nucleoside analog of cytidine. This compound is phosphorylated by cellular enzymes for the formation of emtricitabine 5′-triphosphate. Emtricitabine works to inhibit the activity of the HIV-1 reverse transcriptase (RT) through competing with the natural substrate deoxycytidine 5′-triphosphate and by incorporating it into nascent viral DNA resulting in chain termination. The compound is a weak inhibitor of mammalian DNA polymerase alpha, beta, epsilon, and mitochondrial DNA polymerase gamma.
Tenofovir Disoproxil Fumarate (Emfovir):- It needs initial diester hydrolysis for converting it to tenofovir and subsequent phosphorylations through cellular enzymes for forming tenofovir diphosphate. This compound is particularly an acyclic nucleoside phosphonate diester analog of adenosine monophosphate. It works to inhibit HIV-1 RT activity by competing with the natural substrate deoxyadenosine 5′-triphosphate and, after incorporation into DNA, by DNA chain termination. Tenofovir Disoproxil Fumarate is known to be a weak inhibitor of mammalian DNA polymerases alpha, beta, and mitochondrial DNA polymerase gamma.
Usage Of Emfovir
Emfovir (Tenofovir Disoproxil Fumarate and Emtricitabine) is used to treat patients with HIV (human immunodeficiency virus) and this anti-HIV medicine is a temporary cure. It lowers your risk of getting HIV-related infections. Take this medicine as advised by your physician and try not to miss your regular dosing schedule. Somehow you forgot to take the Emfovir tablet, consult your healthcare provider as soon as possible.
Interactions
Emfovir tablets may interact with other medicines you might take, diseases you have/had, and alcohol. Make sure to read the interactions below before administering the tablets.
Alcohol Interaction
It is not known whether Emfovir interacts with alcohol or not. Consult a qualified medical professional before consuming alcohol with this medicine.
Medicine Interactions
Methotrexate
Tobramycin
Gentamicin
Leflunomide
Efavirenz
Cisplatin
Disease Interactions
Renal dysfunction
Hepatic Impairment
Contraindications
Do not administer Emfovir tablets if you have an allergy to Emtricitabine and Tenofovir Disoproxil Fumarate.
Emfovir tablets are not indicated for use in patients having hypersensitivity.
Emfovir tablets are not recommended for use in patients having kidney impairment.
Alternate Brands
Tofocom
Ricovir EM
Tavin EM
Tenvir EM
Side Effects
Emfovir (Tenofovir Disoproxil Fumarate and Emtricitabine) tablets may cause certain side effects. Make sure to inform a qualified doctor about the same and know the ways to tackle them.
Common Side Effects
Unusual tiredness
Confusion
Cough
Unusual weakness
Indigestion
Constipation
Loss of weight
Nausea
Insomnia
Loss of appetite
Diarrhea
Fever
Chills
Loss of strength
Fatigue
Sore throat
Serious Side Effects
Redness of skin
Blood in urine
Blurred vision
Irregular heartbeat
Seizures
Abnormal dream
Taste changes
Swollen lymph nodes
Dosage
Normal Dose
Take Emfovir tablets as per your doctor’s prescription. Do not adjust the dose on your own. Do not crush, chew, or break the tablets.
Missed Dose
If you miss a dose, be sure to contact your healthcare professional to get the needed guidance. Do not increase the strength of the dose to cope with the skipped dose.
Overdose
If symptoms of overdose occur, be sure to contact your healthcare professional or call an emergency medical helpline. You will be provided with supportive care.
Warnings And Precautions
General Warnings
Tell your doctor about the medicines you already administer, including supplements.
Do not administer Emfovir tablets without a prescription.
Emfovir tablets may cause several allergic reactions in some patients. If you experience such side effects, consult a physician.
If you are suffering from liver or/and kidney impairment, do not administer Emfovir tablets without discussing their risks and benefits with your doctor.
Warnings For Females
Pregnancy
During pregnancy, Emfovir tablets may cause harm to the developing baby. It is advised to avoid its administration.
Breastfeeding
During breastfeeding, Emfovir tablets may cause harm to the new-born baby. It is advised to avoid its administration.
Special Precautions
Do not crush or chew Emfovir tablets.
Do not miss a dose of Emfovir.
Adjusting the dose on your own can cause adverse reactions. Do not overdose.
