Brand Name:- Bortecine
Generic Name:- Bortezomib
Manufacturer:- Arechar Healthcare
Strength:- 2 mg
Dosage:- Injection
Storage:- Store at room temperature (10-30°C)
Indication:- Multiple Myeloma and Mantle Cell Lymphoma
Prescription required:- Yes
Overview
Bortecine 2mg injection is an anti-cancer medication, prescribed for the treatment of Multiple Myeloma (a Cancer of Bone Marrow) and Mantle Cell Lymphoma. It is a prescription medicine comprising Bortezomib, an N-protected dipeptide. It is usually recommended for use in combination with other medications. Bortecine (Bortezomib) is given as an injection by the medical practitioner. This medicine works by slowing the multiplication of cancer cells in the human body.
Usage Of Medicine
Bortecine comprises Bortezomib, which is used in the treatment of Multiple Myeloma and Mantle Cell Lymphoma. This medication is given as an injection. It is advisable to not stop taking this medicine without consulting a medical practitioner. Also, your healthcare provider will decide the dose strength and duration of this medication according to your current medical condition and medical history. Make sure to disclose the details of medicines you already take (including supplements) for better guidance.
Pharmacodynamics
Bortezomib targets the ubiquitin-proteasome pathway which is an essential molecular pathway regulating intracellular concentrations of proteins and promoting protein degradation. The ubiquitin-proteasome pathway is dysregulated in pathological conditions, which leads to aberrant pathway signaling and the formation of malignant cells. The molecular formula of Bortezomib is C19H25BN4O4. Its molecular mass is 384.237 g/mol.
Interactions
All the medicines interact in different manners from person to person. Therefore, it is advisable to consult a healthcare professional to discuss this before the consumption of any new medicine.
Interaction With Alcohol
Interaction with alcohol is unknown. Therefore, be sure to consult your doctor.
Interaction With Medicines
- Nitrofurantoin
- Insulin
- Infliximab
- Clozapine
- Metformin
Disease Interactions
- Diabetes
- Hepatotoxicity
- Cardiac Toxicity
- Pulmonary toxicity
- Hypotension
Contraindication
- Bortecine 2mg injection is not indicated to the patients having an allergy to Bortezomib or the inactive ingredients of this medicine.
Alternate Brands
- Bortero
- Bortetrust
- Bortezom
The side effects of Bortecine (Bortezomib) injection are mentioned below. It is important to consult a medical practitioner in case these/other side effects occur.
- Fever
- Chills
- Back pain
- Cough
- Constipation
- Diarrhea
- Vomiting
- Blurred vision
- Bleeding gums
- Fatigue
- Tiredness
- Weakness
- Drowsiness
- Sore throat
- Skin rash
- Itching
- Fainting
- Dizziness
- Insomnia
- Difficulty in breathing
- Pain or redness on injection site
- Decreased appetite
- Peripheral neuropathy (numbness in feet or hands)
- Neutrophils (decrease in white blood cell count)
- Anemia (decrease in red blood cell count)
Normal Dose
It is advisable to not self–administer Bortecine (Bortezomib) injection. Your healthcare provider will give you this injection according to your medical condition.
Missed Dose
Initially, it is advisable to not miss a dose. However, if such a case happens, make sure to consult your healthcare provider to schedule an appointment for the same or guide you further.
Overdose
In case you experience symptoms of overdose, immediately call your doctor or any other medical emergency helpline.
Pregnancy Or Breastfeeding
During Pregnancy or Breastfeeding, Bortecine (Bortezomib) injection is not prescribed for use unless necessary. It is advisable to consult your doctor regarding the potential risks and benefits of this injection.
Driving
After taking Bortecine (Bortezomib) injection, side effects like blurred vision or tiredness may occur. Hence, it is advised to avoid any such activity that demands high concentration (including driving and operating heavy machinery).
Heart Or Respiratory Disease
Bortecine (Bortezomib) injection should be administered with caution in patients having a known heart or respiratory disease (including diabetes). Prior discussion with the doctor about the risks and benefits is recommended.
Things To Avoid
- Alcohol
- Driving
- Unwashed fruits and vegetables
- Raw meat
