Indication
Bendamustine is used to treat Chronic Lymphocytic Leukemia (CLL) that is a type of cancer of the white blood cells. It is also indicated for a type of Non-Hodgkin’s Lymphoma.
Note
SIDE EFFECTS :
- Low blood counts : white and red blood cells and platelets may temporarily decrease
- Increase in bilirubin levels.
- Common side effects include: Infusion reaction (chills, fever, itching, rash), Fever, Nausea, Vomiting, Fatigue, Diarrhea, Rash.
INTERACTIONS :
Tell your doctor about all the medicines you take, including prescription and nonprescription medicines, vitamins and herbal supplements. Especially tell your doctor if you take:
- Medications that block the enzyme CYP1A2 such as Zileuton, Amiodarone, Mexiletine, Propafenone, Verapamil, Cimetidine, Famotidine, Birth control pills, Acyclovir, Ticlopidine, Ciprofloxacin and Fluvoxamine.
- Medications that increase the activity of the enzyme CYP1A2 such as Montelukast, Phentoin, Omeprazole, Phenobarbital.
- Cigarette smoking may decrease the effectiveness of Bendamustine
OVERDOSE :
If this medication is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur. However, if an overdose is suspected, seek emergency medical attention.
Precaution
- Bendamustine is a prescription drug and should be used under proper medical guidance and advice.
- Bendamustine may cause Myelosuppression & lead to some infections.
- Bendamustine may lead to renal failure and anaphylactic reaction.
- Use in pregnancy should be avoided.
