Overview
Aromasin is an anti-cancer medicine. It is approved for the treatment of estrogen receptor-positive breast cancer in postmenopausal women. This medication comprises exemestane (an antineoplastic aromatase inhibitor). It is available in the form of oral tablets of strength 25mg. In some cases, it is also used as an adjuvant treatment for breast cancer. It is usually given to women who have received two to three years of tamoxifen. This drug is taken orally as per the strength prescribed by the doctor.
Pharmacodynamics
Aromatase is an enzyme found in the adrenal glands that transform hormones into estrogen. Aromatase inhibitors (AIs) like Aromasin (Exemestane) are medications that limit the function of aromatase in the adrenal glands, lowering estrogen levels. Selective AIs (SAIs) lower estrogen levels while leaving other steroid hormones generated by the adrenal gland alone.
Interactions
Aromasin (Exemestane) tablets may interact with these:
Medicine Interactions
- Thalidomide
- Secobarbital
- Oxcarbazepine
- Lorlatinib
- Carbamazepine
- Fostamatinib
- Amobarbital
Disease Interactions
- Osteoporosis
- Vitamin D deficiency
Alcohol Interactions
- Do not drink alcohol during your treatment with Aromasin (Exemestane) tablets. It may interact with this drug.
Contraindications
It is advisable to not take Aromasin (Exemestane) tablets under the following conditions.
- Low vitamin D levels
- Pregnancy
- Breastfeeding
- Low bone density
Alternate Brands
The following are some alternatives to Aromasin (Exemestane) tablets.
- Xmalon
- Xemasin
- Exetraz
- Exeget
The following are some common adverse effects of taking Aromasin (Exemestane) tablets. Contact your healthcare provider if you have any such concerns.
- Decreased urine output
- Diarrhea
- Headache
- Sore throat
- Difficulty with speaking
- Joint pain
- Loss of hair
- Runny nose
- Stomach upset
- Dilated neck veins
- Dizziness
- Slow speech
- Unpleasant breath odor
- Hot flashes
- Unusual tiredness
- Vomiting of blood
- Weight gain
- Yellow eyes or skin
- Double vision
Take Aromasin (Exemestane) tablets as per the prescription provided by your doctor. Plus, make sure to not cut or chew the tablets during administration.
Missed Dose
If you forget to take a dose of Aromasin (Exemestane) tablets, consult your doctor. Don’t double up the next dose to cope with the missed one unless your doctor recommends it.
Overdose
An overdose on Aromasin (Exemestane) tablets can lead to severe side effects. These may include chest pain and fainting. Kindly contact your nearest doctor immediately.
General warnings
- Tell your medical practitioner about the medicines you take and the diseases you may have already. This helps in making the right decisions about your treatment plan.
- Do not drink alcohol during your treatment with Aromasin (Exemestane) tablets. It may interact with this drug.
- Use effective contraception during sexual intercourse when you are on therapy with Aromasin tablets.
- If you have an existing liver or kidney disease, administer Aromasin tablets with extreme caution.
Warnings For Females
- Pregnancy
- During pregnancy, the use of Aromasin (Exemestane) tablets may not be safe. Contact your medical practitioner to know the risks of using this drug.
- Breastfeeding
- During breastfeeding, the use of Aromasin (Exemestane) tablets may not be safe. Contact your medical practitioner to know the risks of using this drug.
Precautions
- Do not administer Aromasin (Exemestane) tablets without a prescription.
- Do not cut or chew this medication while administering.
- Store this drug away from children’s reach.
- Keep Aromasin tablets away from direct moisture and heat.
