Amiphos (300 mg, 500 mg.)

Dabur Pharmaceuticals Ltd

“Amiphos” contains Drug / Molecule called “Amifostine”. Amiphos is a cytoprotective adjuvant used in cancer chemotherapy involving DNA-binding chemotherapeutic agents.

Amifostine is an organic thiophosphate prodrug which is hydrolysed by alkaline phosphatase to the active cytoprotectivethiol metabolite. The selective protection of non-malignant tissues is believed to be due to higher alkaline phosphatase activity, higher pH, and vascular permeation of normal tissues.

Category:

Indication

Amiphos is used therapeutically to reduce the incidence of neutropenia-related fever and infection induced by DNA-binding chemotherapeutic agents including alkylating agents (e.g. cyclophosphamide) and platinum-containing agents (e.g. cisplatin). It is also used to decrease the cumulative nephrotoxicity associated with platinum-containing agents. Amiphos is also indicated to reduce the incidence of xerostomia in patients undergoing radiotherapy for head and neck cancer.

Note

Precaution

  • Amiphos is a prescription drug and should be used under proper medical guidance and advice.
  • Hypotension during infusion.
  • Caution when used during Pregnancy and Lactation.

 

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