Brand Name:- Alecensa
Generic Name:- Alectinib
Manufacturer:- Gentech
Dosage Form:- Capsules
Strength:- 150mg
Composition:- Alectinib
Packaging:- 240 capsules
Indication:- Lung cancer
Storage Conditions:- Store at room temperature
Overview
Alecensa is a prescribed medicine used to treat people with non-small cell lung cancer that has spread from your lungs to other parts of your body and is caused by an abnormal anaplastic lymphoma kinase ALK gene. Alecensa contains the active drug alectinib, which is an ALK inhibitor. This type of drug is commonly used to treat specific types of cancer. This medicine comes in the form of capsules that are taken orally twice a day with food.
Pharmacodynamics Of Alecensa (Alectinib)
When taken with food, Alecensa reaches peak concentrations approximately 4 hours after dosing. It is metabolized by CYP3A4 to the active metabolite M4. Alecensa targets downstream communication and protein signaling that results from ALK phosphorylation and ALK mediated activation.
Side Effects Of Alecensa (Alectinib)
Alecensa (alectinib) can cause some unwanted side effects :-
Common Side Effects
- Chest pain
- Increased blood pressure
- Bloody urine
- Anemia
- Constipation
- Joint pain
- Loss of appetite
- Muscle and bone pain
- Weakness
- Vomiting
- Weight gain
- Nausea
- Dizziness
- Skin rash
- Allergic reaction
- Bloody stools
- Fever
- Headache
- Irregular heartbeat
- Bloating
- Blurred vision
Serious Side Effects
- Kidney damage
- Liver damage
- Vision problem
- Muscle weakness
- Hyperglycemia
- Pancreatitis
Note- immediately contact your doctor,if any of these symptoms occurs
Alecensa comes in the form of capsules that are taken by mouth. It should be taken twice a day with food.
Missed Dose
- In case you miss a dose immediately contact your doctor. Do not double the dosage to make up for the missed dose.
Overdose
- Emergency medical treatment required or contact your doctor in case of an overdose.
Warnings
Before using Alecensa (alectinib) capsules, inform your doctor about medical history.
- Contraception
- Use reliable methods of contraception to prevent pregnancy while taking this medicine.
- Children and adolescents
- This medicine is not for use in children and adolescents
Warnings For Female
- Pregnancy
- Alecensa shouldn’t be used by women who are pregnant. This medicine may cause harm in human fetuses. It is recommended that drugs should be avoided during pregnancy.
- Breastfeeding
- This medicine should not be used by women who are breastfeeding.
General Warnings And Precautions
- Before starting treatment with Alecensa, make sure you tell your doctor any other medications you are taking.
- Tell your doctor if you have any history of kidney or liver problems.
- If you have lung problems or breathing problems. Do not take this medicine without your doctor’s advice.
- If you have a slow heart rate, Alecensa can worsen your condition.
Cautions
- Do not chew this medicine
- Not safe for pregnant women
- May harm liver
- It’s possible to have bradycardia
