Brand name – Abamune L
Generic name – Abacavir/Lamivudine
Manufacturer – Cipla Ltd
Strength – 600mg/300mg
Dosage – Tablet (Oral administration)
Packaging – Bottle
Indication – HIV infection
Prescription needed – Yes
Description
Abamune L (Abacavir/Lamivudine) tablet is a prescription medicine. It is used in the treatment of HIV (Human Immunodeficiency Virus) infection. It boosts up the immunity to fight against the virus and manage AIDS (Acquired Immunodeficiency Syndrome). It slows the growth of the virus in the body and reduces HIV-related symptoms, thereby improving the lifespan of individuals. It increases the CD4 cell (white blood cells that protect against infection) count in the blood. This medicine is available at the best price in India.
Pharmacodynamics
Abacavir:- Abacavir is a nucleoside reverse transcriptase inhibitor (NRTI) with activity against Human Immunodeficiency Virus Type 1 (HIV-1). It is phosphorylated to active metabolites that compete for incorporation into viral DNA. They work to inhibit the HIV reverse transcriptase enzyme competitively and act as a chain terminator of DNA synthesis.
Lamivudine:- A nucleoside reverse transcriptase inhibitor (NRTI) with activity against Human Immunodeficiency Virus Type 1 (HIV-1) and Hepatitis B (HBV) to disrupt viral DNA synthesis. Lamivudine can form active metabolites when phosphorylated, that compete for incorporation into viral DNA. Via DNA incorporation, lamivudine metabolites inhibit the activity of the HIV reverse transcriptase enzyme and then act as a chain terminator of DNA synthesis.
Usage Of Medicine
Abamune L is a combination of two antiretroviral agents namely Abacavir and Lamivudine. This medicine is available in the strength of 600 mg/300 mg in the form of tablets for oral administration. It is important to take this medicine regularly at the right time for better efficacy. Also, it is advisable to not miss a dose. Make sure to report the side effects to the doctor (if any).
Interactions
Medicine interactions should be discussed with the healthcare provider before taking the Abamune L (Abacavir/Lamivudine) tablet.
Interaction With Alcohol
Interaction with alcohol is unknown. Make sure to consult your healthcare provider before its consumption.
Interaction With Medicines
- Ribavirin
- Efavirenz
- Epirubicin
- Methotrexate
Disease Interaction
- Cardiovascular disease
- Renal Dysfunction
Contraindication
- Abamune L (Abacavir/Lamivudine) tablet is not indicated to patients having a known allergy to any of the active or/and inactive ingredients.
- This tablet is not indicated to patients who are known to be hypersensitive.
Alternate Brands
- Albavir Tablet
- A Bec L 600 mg/300 mg Tablet
- Abalam Tablet
Following are the side effects of Abamune L tablet. Note that there can be other side effects also. Therefore, it is advisable to consult a medical practitioner if side effects occur or last longer than usual.
- Fever
- Chills
- Chest pain
- Cough
- Depression
- Weight loss
- Confusion
- Stomach ache
- Pale skin
- Nausea
- Vomiting
- Diarrhea
- Headache
- Abnormal dreams
- Flatulence
- Drowsiness
- Dizziness
- Insomnia
- Skin rash
- Itching
- Stuffy nose
Normal Dose
Take Abamune L (Abacavir/Lamivudine) tablet exactly as prescribed by the doctor for better efficacy without increasing or decreasing the dose strength. Swallow the tablet as a whole with water, without breaking, cutting, or chewing it.
Missed Dose
It is advisable to not skip a dose. If you miss a dose, make sure to take it as soon as you remember. However, if it is already the time for your next scheduled dose, skip the missed dose and take the scheduled dose. Also, make sure to not increase the dose strength to catch up with the missed dose.
Overdose
It is advisable to not overdose. In case of overdose, be sure to consult your healthcare professional immediately.
Pregnancy Or Breastfeeding
It is advisable to consult the healthcare provider before the consumption of Abamune L (Abacavir/Lamivudine) tablet during pregnancy or breastfeeding because this medicine may harm the baby.
Driving
After the consumption of Abamune L (Abacavir/Lamivudine) tablet, it is advisable to avoid driving or operating heavy machinery if side effects (like blurred vision, lack of concentration) occur.
Liver Or Kidney Disease
It is advisable to administer Abamune L (Abacavir/Lamivudine) tablet with utmost caution in the patients having a known liver or/and kidney disease.
Medical History
Make sure to consult your healthcare provider regarding your medical history, medicines you already take (including supplements), and your current medical condition before consuming Abamune L (Abacavir/Lamivudine) tablet.
