Brand Name: Sunicine
Generic Name: Sunitinib
Manufacturer: Arechar
Strength: 50mg
Dosage: Capsule
Composition: Sunitinib
Indication: Kidney Cancer and Gastrointestinal Stromal Tumor
Storage: Store at room temperature
Overview
Sunicine (Sunitinib) capsule is used in the treatment of Kidney cancer and Gastrointestinal Stromal Tumor. This medication belongs to antineoplastic (cancer-fighting medications) and more specifically to a class of medications known as a tyrosine kinase inhibitor. It is important to take Sunicine capsule as prescribed by your doctor. The recommended dose of Sunicine capsule is decided by a doctor according to your previous medical condition and response to the treatment. If you experience any signs and symptoms while receiving Sunicine medication, inform your doctor immediately.
Pharmacodynamics
Sunitinib is a small molecule that inhibits multiple RTKs, some of which are implicated in tumor growth, pathologic angiogenesis, and metastatic progression of cancer. It inhibits cellular signaling by targeting multiple RTKs. These include all platelet-derived growth factor receptors (PDGF-R) and vascular endothelial growth factor receptors (VEGF-R). After the oral administration, the effect of this medicine can be observed within 6 to 12 hours.
Usage
Sunicine capsule interferes with the growth of cancer cells and destroys them. It works by blocking the activity of tyrosine kinase inhibitors which help to reduce the size of tumors and prevents them from multiplying. Do not take Sunicine capsule in the wrong way as it may lead to some serious side effects. It is advised not to change your regular dosing schedule without taking suggestions from your doctor. Regular monitoring of blood pressure is required during treatment with this medication. Follow the instructions given by your healthcare provider to avoid any further complications.
Interactions
Sunicine capsules can interact with other medications and it may increase the risk for side effects. Don’t forget to disclose and discuss your previous medical history with the doctor.
Medicine Interactions
- Clozapine
- Amiodarone
- Enzalutamide
- Lomitapide
- Pimozide
- Efavirenz
Disease Interactions
- Liver disease
- Hypertension
- Thyroid disorders
- ONJ (Osteonecrosis of the jaw)
- Impaired kidney function
- Bleeding
- Hypoglycemia
- Lung toxicity
Alcohol Interaction
- Interaction with alcohol is unknown. Please consult your doctor before consuming alcohol.
Contraindication
- Do not take this medicine if you are allergic to Sunicine.
- Sunicine (Sunitinib) capsule is not recommended in patients known to be hypersensitive.
Side Effects
This medicine may cause some common side effects. Discuss the risks and benefits of Sunicine capsule with the doctor before starting the treatment.
Common Side Effects
- Dizziness
- Blurred vision
- Cough
- Nausea
- Weakness
- Rash
- Fever
- Abdominal pain
- High blood pressure
- Stomatitis
- Back pain
- Taste change
- Weight loss
- Indigestion
- Bleeding gums
- Thyroid imbalances
- Loss of appetite
- Constipation
- Tiredness
- Diarrhea
- Fatigue
- Hair loss
- Bruising
- Difficulty in breathing
- Allergic reaction
- Discoloration of skin
- Joint pain
- Blisters on hand and feet
- Pain in extremity
- Swelling
Note – immediately contact your healthcare provider if any side effects occur.
Dosage
Take this medicine as prescribed by your doctor. Do not stop or skip your regular dosing schedule of Sunicine capsules.
Missed Dose
- It is advisable not to miss a dose. If you miss a scheduled dose of Sunicine medicine, contact your doctor immediately.
Overdose
- In case of an overdose of Sunicine capsules, the doctor will provide emergency medical treatment.
Warnings
Before starting treatment with Sunicine medicine, please inform your doctor about your previous medical history. If you experience any signs and symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk.
- Contraception
- Use suitable methods of contraception to prevent pregnancy while taking Sunicine capsules.
- Children and adolescents
- Sunicine (Sunitinib) capsules are not recommended for use in children under the age of 18.
Warnings For Female
- Pregnancy
- Do not use Sunicine medicine if you are planning to become pregnant. Avoid this medication at the time of pregnancy.
- Breastfeeding
- Sunicine (Sunitinib) capsules are not recommended in breastfeeding unless it is required. Please consult with your doctor before starting treatment with this medication.
Precautions
- Sunicine medication should be used with caution because it may increase the risk of serious skin reactions.
- Close monitoring of liver function and kidney function is required during treatment with this medication.
- This medication is not recommended for use in patients with low neutrophil counts and platelet counts.
- Sunicine capsules may affect the immune system.
Cautions
- Do not drive or operate heavy machinery.
- Do not break or open the capsule.
- Not safe for pregnant women.
- Do not breastfeed while receiving this medication.
