Brand Name:- Doxotero
Generic Name:- Doxorubicin
Manufacturer:- Hetero
Dosage Form:- Injection
Strength :- 10mg
Composition:- Doxorubicin
Packaging Size:- 1 vial
Indication:- Lung, prostate, pancreatic, bladder, ovarian, head and neck cancer.
Storage Conditions:- Store at room temperature.
Doxotero (doxorubicin) injection is an anticancer agent that is used in the treatment of certain cancers (blood, breast, ovarian, lung, prostate, head and neck). Close monitoring of blood cell counts and kidney function is necessary while receiving this medication. It is given by your doctor or nurse. Before taking this medication tell your doctor if you have any medical history.
Pharmacodynamics Of Doxotero
Doxotero is a long-circulating pegylated liposomal formulation of doxotero HCI that provides a greater concentration of Kaposi’s sarcoma tumor than in normal skin. Pegylated liposomes contain surface-grafted segments of the hydrophilic polymer methoxy polyethylene glycol (MPEG). MPEG groups extend from the liposome surface creating a protective coating that reduces interactions between the lipid bilayer membrane and the plasma components.
Advantages Of Doxotero (Doxorubicin)
- This medication helps to treat certain kinds of cancers.
- This injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells.
- This medication also helps in the treatment of cancer that affects the plasma cells (a type of blood cell) inside the bone marrow.
Substitutes Of Doxotero (Doxorubicin) Injection
- Doxutec
- Adrim
- Prubicin
- Doxilyd
- Adriamycin
Side Effects Of Doxotero (Doxorubicin) Injection
Some of the common side effects of doxorubicin are listed below:-
Common Side Effects
- Vomiting
- Allergic reaction
- Constipation
- Mouth sore
- Loss of appetite
- Hair loss
- Diarrhea
- Weight loss
- Stomach pain
- Eye disorder
- Swelling of the feet
- Weakness
Serious Side Effects
- Skin rash
- Fever with chills
- Pain at the injection site
- Decrease in white blood cell
- Decrease in platelets
Note – consult your doctor immediately if any of these side effects occur
Missed Dose
- In case you miss a dose immediately contact your doctor. Do not double the dosage to make up for the missed dose.
Overdose
- Emergency medical treatment is required or contact your doctor in case of an overdose.
Usage Of Doxotero (Doxorubicin)
Doxorubicin injection is prescribed by the doctors to use in the treatment of ovarian cancer (affects the female reproductive system), breast cancer, Hodgkin’s disease (affects the immune system), multiple myeloma (affects the plasma cells inside the bone marrow). It works by suppressing the activity of an enzyme (topoisomerase II) involved in DNA multiplication of the cancer cells. It also forms harmful chemicals (free radicals) that cause DNA damage. This slows the growth of cancer cells and eventually kills them.
Before using Doxotero (doxorubicin) injection, inform your doctor about your medical history.
- Contraception
- Use reliable methods of contraception to prevent pregnancy while taking this medicine.
- Children and adolescents
- This medicine is not for use in children and adolescents
Warnings For Female
- Pregnancy
- Docetero (docetaxel) injection is unsafe during pregnancy. It may cause harm to the unborn baby.
- Breastfeeding
- Docetero (docetaxel) injection is unsafe during breastfeeding.
General Warnings And Precautions
- Patients with a history of heart disease need close monitoring while receiving this medicine.
- This medication can increase the chance of infection and bleeding.
- Close monitoring of the blood cell count is necessary. Do not start this treatment if the blood cell count is low.
- This medication can increase the risk of secondary cancers, most frequently in the mouth.
- Avoid body fluids.
Cautionary Labels
- Not safe for pregnant women.
- Not safe during breastfeeding.
- May decrease blood count
- May harm liver
