Brand Name: Tafero-EM
Generic Name: Emtricitabine and Tenofovir disoproxil fumarate
Manufacturer: Hetero
Dosage Form: Tablet
Strength: 200mg/25mg
Composition: Emtricitabine (200mg) and Tenofovir disoproxil fumarate (25mg)
Indication: HIV
Packaging: 30 tablets
Storage: Store at room temperature
Overview
Tafero EM tablet is a combination of two anti-HIV medicines: Emtricitabine and Tenofovir disoproxil fumarate. This medication is used for the treatment of HIV (human immunodeficiency virus) infection. It belongs to a class of medication known as nucleoside reverse transcriptase inhibitors (NRTIs). Tafero EM tablet boosts your immune system to fight against infection and prevents the virus from multiplying. It increases the CD4 cell (white blood cells that protect against infection) count in your blood. It is important to take this medicine as prescribed by your doctor. It is advised not to change your regular dosing schedule without taking suggestions from your doctor.
Pharmacodynamics
Emtricitabine (Tafero EM):- a synthetic nucleoside analog of cytidine, is phosphorylated by cellular enzymes to form emtricitabine 5′-triphosphate. Emtricitabine inhibits the activity of the HIV-1 reverse transcriptase (RT) by competing with the natural substrate deoxycytidine 5′-triphosphate and by being incorporated into nascent viral DNA which results in chain termination.
Tenofovir Disoproxil Fumarate (Tafero EM):- Tenofovir disoproxil fumarate is an acyclic nucleoside phosphonate diester analog of adenosine monophosphate. It requires initial diester hydrolysis for conversion to tenofovir and subsequent phosphorylations by cellular enzymes to form tenofovir diphosphate. Tenofovir disoproxil fumarate inhibits the activity of HIV-1 RT by competing with the natural substrate deoxyadenosine 5′-triphosphate and, after incorporation into DNA, by DNA chain termination.
Usage
Tafero EM (Emtricitabine and Tenofovir Disoproxil Fumarate) tablet is a combination of two antiretroviral medications. It helps to delay the production of HIV infection and improves the quality of life. This medication is not a permanent cure for HIV infection. It only prevents the multiplication of HIV (human immunodeficiency virus) infection in human cells. The recommended dose of Tafero EM medicine is decided by a doctor according to your previous medical condition and response to the treatment. Do not take this medicine in the wrong way as it may lead to some serious side effects. If you experience any signs and symptoms while receiving Tafero EM tablet, inform your doctor immediately.
Interactions
Tafero EM tablets can interact with other medications and it may increase the risk for side effects. Don’t forget to disclose and discuss your previous medical history with the doctor.
Medicine Interactions
- Adefovir
- Cisplatin
- Etidronate
- Leflunomide
- Tobramycin
- Gentamicin
Disease Interactions
- Hepatoxicity
- Renal dysfunction
- Hemodialysis
Alcohol Interaction
- Interaction with alcohol is unknown. Please consult your doctor before consuming alcohol.
Contraindication
- Do not take this medicine if you are allergic to Emtricitabine and Tenofovir disoproxil fumarate.
- Tafero EM tablet is not recommended in patients known to be hypersensitive.
Side Effects
This medicine may cause some common side effects. Discuss the risks and benefits of the Tafero EM tablets with the doctor before starting the treatment.
- Trouble sleeping
- Loss of strength
- Fatigue
- Sore throat
- Swollen lymph nodes
- Loss of appetite
- Seizures
- Cough
- Unusual weakness
- Blurred vision
- Loss of weight
- Nausea
- Insomnia
- Diarrhea
- Blood in urine
- Irregular heartbeat
- Abnormal dream
- Confusion
- Indigestion
- Constipation
- Redness of skin
- Taste changes
- Unusual tiredness
- Fever
- Chills
Note – immediately contact your health care provider or medical practitioner if any side effects occur.
Dosage
Take this medicine as prescribed by your doctor. Make sure to not skip or stop your regular dosing schedule.
Missed Dose
- It is advisable not to miss a dose. If you miss a scheduled dose of Tafero EM tablets, contact your doctor immediately.
Overdose
- In case of an overdose of Tafero EM tablets, the doctor will provide emergency medical treatment.
Warning
Before starting treatment with Tafero EM medicine, please inform your doctor about your previous medical history. If you experience any signs and symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk.
- Contraception
- Use suitable methods of contraception to prevent pregnancy while taking Tafero EM medicine.
- Children and adolescents
- Tafero EM tablets are not recommended for use in children under the age of 18.
Warnings For Female
- Pregnancy
- Do not use Tafero EM medicine if you are planning to become pregnant. Avoid this medication at the time of pregnancy.
- Breastfeeding
- This medicine is not recommended in breastfeeding unless it is required. Please consult with your doctor before starting treatment with Tafero EM (Emtricitabine and Tenofovir Disoproxil Fumarate).
Precautions
- Inform your doctor if you experience any side effects like- nausea, insomnia, fever, sore throat, headache, abnormal dream, anxiety, etc.
- This medication may increase the risk of immune reconstitution syndrome.
- Close monitoring of bone mineral density is required during treatment with this medicine.
- Tafero EM increases the risk of lactic acidosis.
Cautions
- Do not drive or operate heavy machinery.
- Do not crush or break the tablet.
- Not safe for pregnant women.
- Do not breastfeed while receiving this medication.
