Brand Name: Abalam
Generic Name: Abacavir and Lamivudine
Manufacturer: Genix Lifescience
Dosage Form: Tablet
Strength: 600mg + 300mg
Composition: Abacavir (600mg) and Lamivudine (300mg)
Packaging: 30 tablets (30 / Bottle)
Indication: HIV
Storage: Store at room temperature
Overview
Abalam (Abacavir and Lamivudine) tablet is a combination of two antiretrovirals medicines. It is used in the treatment of HIV (human immunodeficiency virus) infection. This medication is not a permanent cure for HIV infection. It helps to boost your immune system to fight against infection and prevents the virus from multiplying and also increases the CD4 cell (white blood cells that protect against infection) count in your blood. It is important to take this medicine as prescribed by your doctor. It is advisable not to change your regular dosing schedule without taking suggestions from your doctor. If you experience any signs and symptoms while receiving this medicine, inform your doctor immediately.
Pharmacodynamics
Abacavir (Abalam):- It is a nucleoside reverse transcriptase inhibitor (NRTI) with activity against Human Immunodeficiency Virus Type 1 (HIV-1). It is phosphorylated to active metabolites competing for incorporation into viral DNA. They work to inhibit the HIV reverse transcriptase enzyme competitively and act as a chain terminator of DNA synthesis.
Lamivudine (Abalam):- It is a nucleoside reverse transcriptase inhibitor (NRTI) with activity against Human Immunodeficiency Virus Type 1 (HIV-1) and Hepatitis B (HBV) to disrupt viral DNA synthesis. It can form active metabolites when phosphorylated, that compete for incorporation into viral DNA. Via DNA incorporation, lamivudine metabolites work to inhibit the activity of the HIV reverse transcriptase enzyme and then act as a chain terminator of DNA synthesis.
Usage
Abalam tablet is a combination of two anti-HIV medicines: Abacavir and Lamivudine. This antiviral medication prevents the human immunodeficiency virus (HIV) from multiplying in your body. This medication helps to delay the production of HIV infection and improves the quality of life. Do not take this medicine in the wrong way as it may lead to some serious side effects. If you experience any signs and symptoms while receiving this medicine, inform your doctor immediately. Do not skip or miss the dosing schedule. This medicine is not recommended in pregnant women. Store this medicine at room temperature. Protect it from moisture and heat.
Interactions
Abalam tablets can interact with other medications and it may increase the risk for side effects. Don’t forget to disclose and discuss your previous medical history with the doctor.
Medicine Interactions
- Bexarotene
- Zalcitabine
- Leflunomide
- Emtricitabine
- Teriflunomide
Disease Interactions
- Hepatoxicity
- Pancreatitis
- Renal impairment
Alcohol Interaction
- Interaction with alcohol is unknown. Please consult your doctor before consuming alcohol.
Contraindications
- Do not take this medicine if you are allergic to Abacavir and Lamivudine.
- Abalam (Abacavir and Lamivudine) medicine is not recommended in patients known to be hypersensitive.
Substitutes
- Albavir
- Abamune L
- A bec L
Side Effect
This medicine may cause some common side effects. Discuss the risks and benefits of the Abalam tablets with the doctor before starting the treatment.
Common Side Effects
- Trouble sleeping
- Loss of strength
- Fatigue
- Sore throat
- Swollen lymph nodes
- Loss of appetite
- Seizures
- Cough
- Unusual weakness
- Blurred vision
- Loss of weight
- Nausea
- Insomnia
- Fever
- Chest pain
- Diarrhea
- Anxiety
- Headache
- Allergic reaction
- Unusual tiredness
- Poor concentration
- Confusion
- Abnormal dreams
- Sensation of spinning
Note – immediately contact your health care provider and medical practitioner if any side effects occur.
Dosage
Take this medicine as prescribed by your doctor. Do not stop or skip your regular dosing schedule.
Missed Dose
- It is advisable not to miss a dose. If you miss a scheduled dose of Abalam tablets, contact your doctor immediately.
Overdose
- In case of an overdose of Abalam tablets, the doctor will provide emergency medical treatment.
Warning
Before starting treatment with Abalam medicine, please inform your doctor about your previous medical history. If you experience any signs and symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk.
- Contraception
- Use suitable methods of contraception to prevent pregnancy while taking Abalam medicine.
- Children and adolescents
- Abalam tablets are not recommended for use in children under the age of 18.
Warnings For Female
- Pregnancy
- Do not use Abalam medicine if you are planning to become pregnant. Avoid this medication at the time of pregnancy.
- Breastfeeding
- This medicine is not recommended in breastfeeding unless it is required. Please consult with your doctor before starting treatment with Abalam (Abacavir and Lamivudine).
Precautions
- Inform your doctor if you experience any side effects like- nausea, insomnia, fever, sore throat, headache, allergic reaction, anxiety, etc.
- This medication is not recommended in patients with severe liver disease.
- Abalam tablet can increase your risk of a heart attack. Special monitoring is needed for such patients.
- Do not skip your regular dosing schedule.
- Close monitoring of heart and liver function is required during treatment with this medication.
Cautions
- Do not drive or operate heavy machinery.
- Do not crush or break the tablet.
- Not safe for pregnant women.
- Do not breastfeed while receiving this medication.
