Medicine Details
Brand name – Altraz
Generic name – Anastrozole
Salt composition – Anastrozole 1 mg
Manufacturer – Alkem Laboratories
Dosage form – Oral (tablet)
Packaging – Strip
Indication – Early breast cancer
Storage – Store at room temperature (10-30°C)
Strength – 1 mg
Prescription required – Yes
Description
Altraz (Anastrozole) tablet is used in the treatment of early breast cancer in postmenopausal women. Altraz Tablet belongs to a class of drugs that are called aromatase inhibitors. It works to decrease the amount of estrogen in the body. Is tablet is used to treat women whose breast cancer has been worsened. Several dose adjustments may be needed in the case of patients who have liver or kidney disease. Administer this tablet only when your healthcare provider prescribes it.
Pharmacodynamics
Pharmacotherapeutic group: Enzyme inhibitors
ATC Code: L02B G03
Altraz (Anastrozole) is a potent and non-steroidal aromatase inhibitor. Estradiol is produced in postmenopausal women through the conversion of androstenedione to estrone via the aromatase enzyme complex in peripheral tissues. Estrone is converted to estradiol. Reducing circulating levels of estradiol has been shown to produce a potential benefit in women who have breast cancer. In postmenopausal women, Altraz at a daily dose of 1 mg has shown to produce estradiol suppression of greater than 80% using a highly sensitive assay. Daily doses of Altraz (Anastrozole) up to 10 mg do not have any measurable effect on aldosterone secretion or cortisol when measured before or after standard adrenocorticotrophic hormone (ACTH) challenge testing. Therefore, Corticoid supplements are not needed.
Interaction
- Interaction with other medicines: Estradiol, Tamoxifen, Thalidomide
- Interaction with alcohol: unknown
- Disease interaction: Cardiovascular Disease, Hyperlipidemia, Liver Disease
Alternate Brands
- Armotraz Tablet
- Femitraz Tablet
- Anabrez Tablet
- Xenosoul Tablet
- Erpr Plus Tablet
There can be certain side effects of Altraz tablets. Make sure to consult your doctor in case you experience any of the following or other side effects.
- Nausea
- Skin rash
- Weakness
- Hot flashes
- Blurred vision
- Chest pain
- Cough
- Weight gain or loss
- Sore throat
- Stomach pain
- Loss of appetite
- Shortness of breath
- Joint pain
- Altraz is usually not prescribed during pregnancy because it can harm the developing baby. Make sure to consult your doctor.
- Altraz is not safe for use during breastfeeding.
- Take the dose exactly as your doctor tells you.
- Do not drive or operate heavy machinery if you experience side effects that make you feel unwell or dizzy.
- Altraz tablet should be given with utmost caution to patients having a known liver/kidney disease.
