Brand Name:- Doxorubicin
Generic Name:- Doxorubicin Hydrochloride
Manufacturer:- Pfizer
Dosage Form:- Injection
Strength:- 200mg/100ml
Composition:- Doxorubicin Hydrochloride
Packaging:- 1vial
Indication:- Ovarian cancer, Kaposi’s sarcoma, and multiple myeloma
Storage:- Store this medicine in the refrigerator.
Overview
Doxorubicin is used to treat certain types of cancer (ovarian cancer, AIDs related to Kaposi’s sarcoma, and multiple myeloma). This medication belongs to the group of antineoplastics (cancer-fighting medications) known as anthracyclines. Doxorubicin medicine works by slowing or stopping the growth of cancer cells. Take this medicine as prescribed by your medical advisor. Dosage is based on your medical condition and your response to the treatment. This medicine is given as an infusion into your vein. Do not self administer this medicine. Do not take this medicine in the wrong way as it may lead to some severe side effects. If you experience any symptoms while receiving this medicine, inform your doctor immediately.
Pharmacodynamics Of Doxorubicin
Doxorubicin is an antineoplastic in the anthracycline class. Doxorubicin forms complexes with DNA by intercalation between base pairs, and it inhibits topoisomerase II activity by stabilizing the DNA-topoisomerase II complex, preventing the relegation portion of the ligation-relegation reaction that topoisomerase II catalyzes.
Usage Of Doxorubicin
It is an anti-cancer medication that is used for the treatment of blood, ovaries, and Kaposi’s sarcoma (a type of cancer that causes lesions to grow below the surface of the skin, lymph nodes, etc.) It can lower blood cells that help your body to fight infections. This medicine must be given slowly as an infusion into the vein. It is important to take this medicine exactly as prescribed by your medical advisor. Do not skip or miss the dosing schedule. It is advisable not to change or stop the dose without taking suggestions from your doctor. Do not use this medicine if you are pregnant.
Side Effects Of Doxorubicin
This medicine may cause some major and minor side effects. Discuss the risks and benefits of this medication with the doctor before starting the treatment.
Common side effects
- Severe headache
- Rash
- Sore throat
- Nausea
- Fever
- Vomiting
- Pain at the injection site
- Dizziness
- Muscle pain
- Diarrhea
- Hair loss
- Cough
- Loss of appetite
- Constipation
- Blisters
- Anxiety
- Shortness of breath
- Tiredness
- Abdominal pain
- Chest pain
- Shortness of breath
- Irregular heartbeat
- Back pain
- Difficulty in urination
- Pale skin
- Fever with chills
- Dehydration
- Mouth ulcers
- Painful blisters on hand and feet
- Low blood pressure
- Pin when eating and swallowing
- Red spots on the skin
- Drowsiness
- Low red and white blood cells
- Blurred vision
- Red and itchy eyes
Note- immediately contact your doctor if any side effects occur.
Dosage Of Doxorubicin
Take this injection as prescribed by your doctor. The injection is given as an infusion into your vein by a doctor or nurse. Do not self administer.
Missed Dose
- It is advisable not to miss a dose. If you miss an appointment for a scheduled dose of this medicine, contact your doctor immediately.
Overdose
- In case of an overdose, the doctor will provide emergency medical treatment.
Warnings Of Doxorubicin
Before starting treatment with Doxorubicin, please inform your doctor about your previous medical history. If you experience any symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk.
- Contraception
- Use effective methods of contraception to prevent pregnancy while taking this medicine.
- Children and adolescents
- This medicine is not advisable for use in children and adolescents.
Warnings For Female
- Pregnancy
- Do not use Doxorubicin if you are pregnant or planning to become pregnant. Avoid this medication at the time of pregnancy.
- Breastfeeding
- This medicine is not recommended in breastfeeding unless it is necessary. Please consult your medical advisor before starting treatment with this medication.
Precautions Of Doxorubicin
- This medicine may increase the risk of heart failure.
- Close monitoring of blood cell count and body temperature is necessary while receiving this medication.
- The use of this medicine may decrease the white blood cell count in patients.
- Do not receive any vaccines while having treatment with this medicine.
- Avoid contact with people who have infections.
- Close monitoring of symptoms like mouth ulcers and bleeding is required.
Cautions Of Doxorubicin
- Not safe for pregnant women.
- Do not drive or operate heavy machinery.
- Do not self administer this medicine.
- Do not breastfeed while receiving this medication.
- Do not start the treatment if the blood cell count is low
