Treanda-bendit (100 mg)

Cephalon

“Treanda” contains the Drug / Molecule “Bendamustine Hydrochloride”. Treanda belongs to a class of medications known as alkylating agents. Alkylating agents are most active in the resting phase of the cell-cycle. There are several types of alkylating agents. Bendamustine is a nitrogen mustard derivative and is active against resting as well as dividing cells.

Indication

Treanda is used to treat Chronic Lymphocytic Leukemia(CLL) that is a type of cancer of the white blood cells. It is also indicated for a type of Non-Hodgkin’s Lymphoma.

Note

SIDE EFFECTS :

  • Low blood counts : white and red blood cells and platelets may temporarily decrease
  • Increase in bilirubin levels.
  • Common side effects include: Infusion reaction (chills, fever, itching, rash), Fever, Nausea, Vomiting, Fatigue, Diarrhea, Rash.

INTERACTIONS :

Tell your doctor about all the medicines you take, including prescription and nonprescription medicines, vitamins and herbal supplements. Especially tell your doctor if you take:

  • Medications that block the enzyme CYP1A2 such as Zileuton, Amiodarone, Mexiletine, Propafenone, Verapamil, Cimetidine, Famotidine, Birth control pills, Acyclovir, Ticlopidine, Ciprofloxacin and Fluvoxamine.
  • Medications that increase the activity of the enzyme CYP1A2 such as Montelukast, Phentoin, Omeprazole, Phenobarbital.
  • Cigarette smoking may decrease the effectiveness of Bendamustine

OVERDOSE :

If this medication is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur. However, if an overdose is suspected, seek emergency medical attention.

Precaution

  • Treanda is a prescription drug and should be used under proper medical guidance and advice.
  • Treanda may cause Myelosuppression & also lead to some infections.
  • Treanda may lead to renal failure and anaphylactic reaction.
  • Use of Treanda in pregnancy should be avoided.