Sorafenib-sorafenat (200 mg)

NATCO PHARMA LIMITED (INDIA)

“Sorafenib” is the Drug / Molecule content in “Sorafenat”. Sorafenib is a small molecular inhibitor of several tyrosine protein kinases. Sorafenib treatment induces catabolic mechanism that involve cell degradation; which may suppress tumor growth.

Category:

Indication

Sorafenib is used for the treatment of Primary Kidney Cancer (Advanced Renal Cell Carcinoma) and Advanced Primary Liver Cancer.

DOSAGE AND ADMINISTRATION:

Recommended daily dose is 400 mg (2 X 200 mg tablets) taken twice daily without food (at least 1 hour before or 2 hours after a meal).

SCHEDULE H PRESCRIPTION DRUG – CAUTION

To be sold by retail on the prescription of an Oncologist only.

Note

SIDE EFFECT :

  • Most commonly occurring Cardiac Ischemia, infarction, Hemorrhage, Hypertension, Hand-Foot skin reaction and rash, Gastrointestinal perforation, Wound healing complications.

INTERACTIONS :

  • Interaction with Docetaxel & Doxorubicin : Sorafenib can cause increase in plasma concentration of Docetaxel & Doxorubicin

OVERDOSE :

  • There is no specific treatment for Sorafenib overdose. In cases of suspected overdose Sorafenib should be withheld and supportive care instituted.

Precaution

  • Sorafenib is a prescription drug and should be used under proper medical guidance and advice.
  • Caution has to be taken in case of kidney / liver problems, pregnancy and lactation.

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